Humans

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Midwifery students' understanding and knowledge of normal birth before 'delivery' of curriculum.

Midwifery Dec 26, 2017
OBJECTIVE: To generate new knowledge that describes and explains the views and understanding, regarding midwifery and normal birth, that newly enrolled midwifery students hold at the commencement of their midwifery education.
Knowledge Bases Curriculum Western Australia Delivery, Obstetric Education, Nursing, Baccalaureate Middle Aged Surveys and Questionnaires Clinical Competence Students, Nursing Midwifery Nurse Midwives Humans Female Adult Male
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High serum adiponectin is associated with anemia development in chronic kidney disease: The results from the KNOW-CKD study.

Cytokine Dec 26, 2017
BACKGROUND: Adiponectin is an adipokine secreted by adipocytes. A low adiponectin level is a significant risk factor of diabetes mellitus and cardiovascular disease. Recent studies have shown that adiponectin is negatively associated with hematopoies...
(2)
Aged Adult Male Middle Aged Humans Renal Insufficiency, Chronic Prospective Studies Longitudinal Studies Female Anemia Adiponectin
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Characteristics Associated With Decreased or Increased Mortality Risk From Glycemic Therapy Among Patients With Type 2 Diabetes and High Cardiovascular Risk: Machine Learning Analysis of the ACCORD Trial.

Diabetes care Dec 26, 2017
OBJECTIVE: Identifying patients who may experience decreased or increased mortality risk from intensive glycemic therapy for type 2 diabetes remains an important clinical challenge. We sought to identify characteristics of patients at high cardiovasc...
(2)
Cardiovascular Diseases Middle Aged Blood Glucose Diabetes Mellitus, Type 2 Treatment Outcome Risk Factors Aged Adult Sensitivity and Specificity Glycated Hemoglobin Body Mass Index Follow-Up Studies Sample Size Double-Blind Method Humans Machine Learning Biomarkers
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Design and synthesis of cell selective α/β-diastereomeric peptidomimetic with potent in vivo antibacterial activity against methicillin resistant S. Aureus.

Bioorganic chemistry Dec 26, 2017
Design of therapeutically viable antimicrobial peptides with cell selectivity against microorganisms is an important step towards the development of new antimicrobial agents. Here, we report four de novo designed, short amphipathic sequences based on...
Peptidomimetics Phosphatidylglycerols Stereoisomerism Amino Acid Sequence Pseudomonas aeruginosa Humans Phosphatidylcholines Microbial Sensitivity Tests Keratinocytes Erythrocytes Anti-Bacterial Agents Enterococcus faecalis Escherichia coli Acinetobacter baumannii Female Methicillin-Resistant Staphylococcus aureus Hemolysis Mice, Inbred BALB C Animals Lipid Bilayers
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Chemical characterization, antioxidant, genotoxic and in vitro cytotoxic activity assessment of Juniperus communis var. saxatilis.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association Dec 26, 2017
Chemical composition and antioxidative, genotoxic and cytotoxic potential of essential oil (EO) and post-distillation waste (PDW) of Serbian Juniperus communis L. var. saxatilis Pall. was studied in human lung carcinoma (A549) and normal lung fibrobl...
Juniperus Doxorubicin Mutagens Female Cell Division Animals G2 Phase Male Cell Line, Tumor Antineoplastic Agents, Phytogenic Antioxidants Plant Extracts Chromatography, Liquid Humans Rats Drug Screening Assays, Antitumor Apoptosis Tandem Mass Spectrometry Cell Line Gas Chromatography-Mass Spectrometry
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Present therapeutic role of cholesteryl ester transfer protein inhibitors.

Pharmacological research Dec 26, 2017
Therapeutic interventions aimed at increasing high-density lipoprotein (HDL) levels in order to reduce the residual cardiovascular (CV) risk of optimally drug treated patients have not provided convincing results, so far. Transfer of cholesterol from...
(1)
Humans Cholesterol Ester Transfer Proteins Animals Cardiovascular Diseases Anticholesteremic Agents
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Data Mining and Machine Learning Algorithms Using IL28B Genotype and Biochemical Markers Best Predicted Advanced Liver Fibrosis in Chronic Hepatitis C.

Japanese journal of infectious diseases Dec 26, 2017
IL28B single nucleotide polymorphism (rs12979860) is an etiology-independent predictor of hepatitis C virus (HCV)-related hepatic fibrosis. Data mining is a method of predictive analysis which can explore tremendous volumes of information from health...
Liver Cirrhosis Interleukins Genetic Markers Data Mining Hepatitis C, Chronic Interferons Male Middle Aged Genetic Predisposition to Disease Polymorphism, Single Nucleotide Machine Learning Algorithms Retrospective Studies Female Humans
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Phase 1b Study of the Safety, Pharmacokinetics, and Disease-related Outcomes of the Matrix Metalloproteinase-9 Inhibitor Andecaliximab in Patients With Rheumatoid Arthritis.

Clinical therapeutics Dec 26, 2017
PURPOSE: Andecaliximab (GS-5745) is a highly selective monoclonal antibody against matrix metalloproteinase-9 (MMP9), a proteolytic enzyme implicated in the pathogenesis of rheumatoid arthritis (RA). This study assessed the safety and pharmacokinetic...
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Male Middle Aged Arthritis, Rheumatoid Antibodies, Monoclonal, Humanized Antibodies, Monoclonal Infusions, Intravenous Double-Blind Method Matrix Metalloproteinase 9 Antirheumatic Agents Matrix Metalloproteinase Inhibitors Humans Female Aged
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Indoleamine 2,3-Dioxygenase (IDO) Enzyme Links Innate Immunity and Altered T-Cell Differentiation in Non-ST Segment Elevation Acute Coronary Syndrome.

International journal of molecular sciences Dec 26, 2017
Atherosclerosis is a chronic inflammatory disease characterized by a complex interplay between innate and adaptive immunity. Dendritic cells (DCs) play a key role in T-cell activation and regulation by promoting a tolerogenic environment through the ...
(2)
Humans Cells, Cultured Female Aged Non-ST Elevated Myocardial Infarction Cell Differentiation Acute Coronary Syndrome T-Lymphocyte Subsets Indoleamine-Pyrrole 2,3,-Dioxygenase Dendritic Cells Lymphocyte Activation Aged, 80 and over Monocytes Immunity, Innate Adult Male Middle Aged
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Selecting Feature Subsets Based on SVM-RFE and the Overlapping Ratio with Applications in Bioinformatics.

Molecules (Basel, Switzerland) Dec 26, 2017
Feature selection is an important topic in bioinformatics. Defining informative features from complex high dimensional biological data is critical in disease study, drug development, etc. Support vector machine-recursive feature elimination (SVM-RFE)...
(2)
Phenotype Biomarkers Computational Biology Support Vector Machine Disease Humans Algorithms
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