Cortical arousals are brief brain activations that disrupt sleep continuity and contribute to cardiovascular, cognitive, and behavioral impairments. Although polysomnography is the gold standard for arousal detection, its cost and complexity limit us...
Anthracnose, caused by the hemibiotrophic fungal pathogen Colletotrichum sublineola, is a significant constraint to sorghum production worldwide. Developing resistant cultivars is the most sustainable control strategy, but it requires constant additi...
Urban expansion and Land Use Land Cover (LULC) change pose critical challenges for sustainable urban planning and risks to food security. This study analyzes multi-temporal Landsat imagery from 1990 to 2020 for five major cities, Islamabad, Karachi, ...
Biochemical and biophysical research communications
Dec 17, 2025
The dry fruits of Amomum villosum (Av) are a traditional Chinese medicine used for gastrointestinal disease. Aromatic oil has been reported to have anti-tumor properties. However, its therapeutic potential and molecular mechanisms remain unclear. Int...
Journal of chemical information and modeling
Dec 17, 2025
Enzyme kinetic parameters, including , , /, and , are critical for guiding applications in enzyme engineering, metabolic modeling, and synthetic biology by providing quantitative information on enzyme activity under various conditions. Experimental d...
The escalating global burden of Alzheimer's disease (AD), projected to reach $16.9 trillion by 2050 with disproportionate impacts on low- and middle-income countries and racial minorities, underscores an urgent need for accessible early detection too...
Journal of cancer research and clinical oncology
Dec 17, 2025
BACKGROUND: Thyroid cancer (TC) is one of the most prevalent endocrine malignancies, and its recurrence presents a major clinical challenge that can adversely affect patient prognosis and treatment outcomes. Despite the progress in diagnostic methods...
BACKGROUND: Access to routine dental care is a cornerstone of preventive healthcare. Regular dental check-ups, which include professional cleanings, examinations, and preventive treatments, play a crucial role in preventing advanced dental diseases s...
BACKGROUND: Physical activity (PA) has emerged as a promising non-pharmacological intervention for pain management, the relationship between objectively measured PA patterns and multi-site pain remains poorly understood. This exploratory study invest...
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