BACKGROUND: Childhood obesity poses a significant risk to bone health, but the impact of insulin resistance (IR) on bone metabolism in prepubertal children, as assessed by the triglyceride-glucose (TyG) index, remains underexplored. Bone turnover mar...
BACKGROUND: Tuberculous pleural effusion (TPE) is a prevalent tuberculosis complication, with diagnosis presenting considerable challenges. Timely and precise identification of TPE is vital for effective patient management and prognosis, yet existing...
This study introduces a transfer learning framework to address data scarcity in mortality risk prediction for the UK, where local mortality data is unavailable. By leveraging a pretrained model built from data across eight countries (excluding the UK...
Frontiers in cellular and infection microbiology
Jan 1, 2025
Tuberculosis (TB) remains a global health challenge, with timely and accurate diagnosis being critical for effective disease management and control. Recent advancements in the field of TB diagnostics have focused on the identification and utilization...
BACKGROUND: Breast cancer is a heterogeneous malignancy with complex molecular characteristics, making accurate prognostication and treatment stratification particularly challenging. Emerging evidence suggests that lactylation, a novel post-translati...
BACKGROUND: Psoriasis and Crohn's disease (CD) are chronic inflammatory diseases that involve complex immune-mediated mechanisms. Despite clinical overlap and shared genetic predispositions, the molecular pathways connecting these diseases remain inc...
BACKGROUND: Metabolic dysfunction-associated steatohepatitis (MASH) is becoming increasingly prevalent. Regulated cell death (RCD) has emerged as a significant disease phenotype and may act as a marker for liver fibrosis. The present study aimed to i...
AIM: Endometriosis is characterized by immune evasion and progressive inflammation. This study aimed to identify key genes related to immune and inflammation in endometriosis.
This study analyzes 284 publicly listed companies first designated as ST or *ST between 2015 and 2023. It utilizes two types of textual indicators: Management's Discussion and Analysis (MD&A) and stock forum comments. PCA and MLP are employed for dim...
PURPOSE: Voriconazole (VCZ) is a first-line treatment for invasive fungal disease, characterized by a narrow therapeutic window and significant inter-individual variability. It is primarily metabolized by the liver, the function of which declines wit...
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