BACKGROUND: With the widespread adoption of low-dose CT screening, the detection of pulmonary ground-glass nodules (GGNs) has risen markedly, presenting diagnostic challenges in distinguishing preinvasive lesions from invasive adenocarcinomas (IAC). ...
The clinical manifestations of infectious mononucleosis (IM) and acute respiratory tract infections (ARTI) exhibit significant similarities. We aim to develop cost-efficient models for IM in children utilizing the Shapley Additive explanation (SHAP) ...
BACKGROUND: Predicting the prognosis of patients with acute cerebral infarction (ACI) is crucial for clinical decision-making and personalized treatment. However, existing models often lack the comprehensive integration of clinical and biological ind...
OBJECTIVE: To evaluate the effect of deep learning (DL)-based artificial intelligence (AI) software on the diagnostic performance of radiologists with different experience levels in detecting nigrosome 1 (N1) abnormalities on susceptibility map-weigh...
Journal of cellular and molecular medicine
Aug 1, 2025
The immunoregulatory functions and clinical implications of APOE+ macrophages within the tumour microenvironment of lung adenocarcinoma remain incompletely defined. In this study, single-cell transcriptome analysis revealed distinct subsets of APOE+ ...
Neuropathology : official journal of the Japanese Society of Neuropathology
Aug 1, 2025
This study aimed to evaluate the performance of ChatGPT-4.0 as a diagnostic support tool for pathologists in identifying different types of gliomas based on histopathological data and to compare its performance with that of another artificial intelli...
Reconstructing the diets of extinct taxa is essential for understanding their ecologies and evolutionary histories, yet traditional methods and proxies such as molar morphology have limited resolution. The potential of premolar morphology as a dietar...
The management of chronic hepatitis B (CHB) encounters challenges like suboptimal antiviral response and the lack of predictive biomarkers. In this study, the role of paternally expressed gene 10 (PEG10) in hepatitis B e antigen (HBeAg) seroconversio...
BACKGROUND: Glucagon-like Peptide-1 Receptor Agonists (GLP1RA) may reduce asthma exacerbation (AE) risk, but it is unclear which populations benefit most. Recent pharmacoepidemiologic studies have employed iterative causal forest (iCF), a machine lea...
Journal of cachexia, sarcopenia and muscle
Aug 1, 2025
BACKGROUND: The diagnosis of malnutrition has evolved with the GLIM recommendations, which advocate for integrating phenotypic criteria, including muscle mass measurement. The GLIM framework specifically suggests using skeletal muscle index (SMI) ass...
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