Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Jun 1, 2025
The clinical benefits of neoadjuvant chemoimmunotherapy (NACI) are demonstrated in patients with bladder cancer (BCa); however, more than half fail to achieve a pathological complete response (pCR). This study utilizes multi-center cohorts of 2322 pa...
Accurate and timely diagnosis of brain tumors is critical for patient management and treatment planning. Magnetic resonance imaging (MRI) is a widely used modality for brain tumor detection and characterization, often aided by the administration of g...
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
Jun 1, 2025
OBJECTIVES: The resting-state cerebral functional activity underlying chronic insomnia disorder (CID) remains inconsistent, and the effects of pharmacotherapy on such activity are unclear.
The application of AI for predicting critical heart failure endpoints using echocardiography is a promising avenue to improve patient care and treatment planning. However, fully supervised training of deep learning models in medical imaging requires ...
BACKGROUND: Early identification of individuals who progress from normal cognition (NC) to mild cognitive impairment (MCI) may help prevent cognitive decline. We aimed to build predictive models using radiomic features of the bilateral hippocampus in...
Photodiagnosis and photodynamic therapy
Jun 1, 2025
PURPOSE: This study aimed to establish and validate a prediction model based on machine learning methods and SHAP algorithm to predict response to anti-vascular endothelial growth factor (VEGF) therapy in neovascular age-related macular degeneration ...
Gait analysis is crucial for diagnosing and monitoring various healthcare conditions, but traditional marker-based motion capture (MoCap) systems require expensive equipment, extensive setup, and trained personnel, limiting their accessibility in cli...
BACKGROUND: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with increasing prevalence. While genetics play a strong causal role, among environmental factors, air pollution (AP) exposure in pregnancy and infancy has been strongly endo...
BACKGROUND: Gallbladder cancer (GBC) is a rare but aggressive malignancy, often detected late due to early asymptomatic stages. Understanding cellular and molecular changes from normal tissue to high-grade intraepithelial neoplasia (HGIN) and invasiv...
The accurate assessment of pain in clinical settings is challenging due to its subjective nature. In this study, we used functional near-infrared spectroscopy (fNIRS) to measure brain activity by detecting changes in blood oxygenation. Leveraging the...
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