AIMC Topic: Male

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Predicting post-liver transplantation mortality: a retrospective cohort study on risk factor identification and prognostic nomogram construction.

European journal of medical research
BACKGROUND: To identify risk factors for post-transplant mortality and develop a machine learning-integrated prognostic tool to optimise clinical decision-making in liver transplantation (LT) recipients.

Optimizing timing and cost-effective use of plasma biomarkers in Alzheimer's disease.

Alzheimer's research & therapy
BACKGROUND AND OBJECTIVES: Early and cost-effective identification of amyloid positivity is crucial for Alzheimer's disease (AD) diagnosis. While amyloid PET is the gold standard, plasma biomarkers such as phosphorylated tau 217 (pTau217) provide a p...

Effect of discontinuing antipsychotic medications on the risk of hospitalization in long-term care: a machine learning-based analysis.

BMC medicine
BACKGROUND: Antipsychotic medications are frequently prescribed to older residents of long-term care facilities (LTCFs) despite their limited efficacy and considerable safety risks. While discontinuation of these drugs might help reduce their associa...

Cancer care coordination determinants of depression in head and neck cancer survivors.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
PURPOSE: This study aims to explore the role of patient-reported cancer care coordination in explaining depression among head and neck (HNC) cancer survivors.

Integrating miRNA profiling and machine learning for improved prostate cancer diagnosis.

Scientific reports
Prostate cancer (PCa) diagnosis remains challenging due to overlapping clinical features with benign prostatic hyperplasia (BPH) and limitations of existing diagnostic tools like PSA tests, which yield high false-positive rates. This study investigat...

Factors influencing the adoption of generative artificial intelligence into classroom teaching by university teachers: An empirical study using SPSS PROCESS macros.

PloS one
With the development of science and technology, higher education faces the challenge of AIGC. As one of the central bodies of higher education, it is essential to understand whether teachers accept this new technology and what factors influence their...

Predicting in-hospital mortality in ICU patients with lymphoma using machine learning models.

PloS one
BACKGROUND: Lymphoma is a severe condition with high mortality rates, often requiring ICU admission. Traditional risk stratification tools like SOFA and APACHE scores struggle to capture complex clinical interactions. Machine learning (ML) models off...

Deep learning-based spatial analysis on tumor and immune cells of pathology images predicts MIBC prognosis.

PloS one
OBJECTIVE: Muscle-invasive bladder cancer (MIBC) is a highly aggressive disease with a poor prognosis. This study aims to explore the correlation between the spatial distribution of lymphocyte aggregates and the prognosis of MIBC using deep learning.

Anoikis-related genes predicts prognosis and therapeutic response in renal cell carcinoma.

Annals of medicine
BACKGROUND: Metastasis represents the primary cause of cancer-related mortality, with a high incidence observed in renal cell carcinoma (RCC). Anoikis, a specialized form of apoptosis, plays a crucial role in preventing displaced cells from adhering ...

Unraveling Microstructural and Macrostructural Brain Age Dynamics in Multiple Sclerosis.

Neurology(R) neuroimmunology & neuroinflammation
BACKGROUND AND OBJECTIVES: In multiple sclerosis (MS), neurodegeneration results from the interplay between disease-specific pathology and normal aging. Conventional MRI captures morphologic changes in neurodegeneration, while quantitative MRI (qMRI)...