AIMC Topic: Multicenter Studies as Topic

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Does the alternating timing of rTMS combined with soft-hand rehabilitation robot affect the recovery of hand function in patients after stroke? A study protocol for a multicentre randomised controlled trial.

BMJ open Mar 3, 2025
INTRODUCTION: Combining repetitive transcranial magnetic stimulation (rTMS) with robotic training could result in more significant improvements in motor function than either treatment alone. The efficacy of this combination may depend on the sequenci...
Male Middle Aged Time Factors Multicenter Studies as Topic Female Aged Adult Hand Stroke Stroke Rehabilitation Transcranial Magnetic Stimulation Recovery of Function Randomized Controlled Trials as Topic Robotics Single-Blind Method Humans
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A multicentre implementation trial of an Artificial Intelligence-driven biomarker to inform Shared decisions for androgen deprivation therapy in men undergoing prostate radiotherapy: the ASTuTE protocol.

BMC cancer Feb 13, 2025
BACKGROUND: Androgen deprivation therapy (ADT) improves outcomes in men undergoing definitive radiotherapy for prostate cancer but carries significant toxicities. Clinical parameters alone are insufficient to accurately identify patients who will der...
Prognosis Biomarkers, Tumor Male Australia Multicenter Studies as Topic Prostatic Neoplasms Androgen Antagonists Humans Artificial Intelligence
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Clinical validation of an artificial intelligence-based decision support system for diagnosis and risk stratification of heart failure (STRATIFYHF): a protocol for a prospective, multicentre longitudinal study.

BMJ open Jan 7, 2025
INTRODUCTION: Heart failure (HF) is a complex clinical syndrome. Accurate risk stratification and early diagnosis of HF are challenging as its signs and symptoms are non-specific. We propose to address this global challenge by developing the STRATIFY...
Humans Artificial Intelligence Male Middle Aged Risk Assessment Decision Support Systems, Clinical Prospective Studies Prognosis Female Aged Heart Failure Validation Studies as Topic Longitudinal Studies Observational Studies as Topic Multicenter Studies as Topic
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Healthy core: Harmonizing brain MRI for supporting multicenter migraine classification studies.

PloS one Dec 31, 2024
Multicenter and multi-scanner imaging studies may be necessary to ensure sufficiently large sample sizes for developing accurate predictive models. However, multicenter studies, incorporating varying research participant characteristics, MRI scanners...
Case-Control Studies Female Multicenter Studies as Topic Humans Magnetic Resonance Imaging Adult Machine Learning Migraine Disorders Male Brain Middle Aged
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Rationale and design of the GOLDEN BRIDGE II: a cluster-randomised multifaceted intervention trial of an artificial intelligence-based cerebrovascular disease clinical decision support system to improve stroke outcomes and care quality in China.

Stroke and vascular neurology Dec 30, 2024
BACKGROUND: Given the swift advancements in artificial intelligence (AI), the utilisation of AI-based clinical decision support systems (AI-CDSSs) has become increasingly prevalent in the medical domain, particularly in the management of cerebrovascu...
Quality Improvement Quality Indicators, Health Care Multicenter Studies as Topic Randomized Controlled Trials as Topic Ischemic Stroke Clinical Decision-Making Female Male China Time Factors Decision Support Systems, Clinical Treatment Outcome Humans Artificial Intelligence
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Allogenic faecal microbiota transplantation for antibiotic-associated diarrhoea in critically ill patients (FEBATRICE)-Study protocol for a multi-centre randomised controlled trial (phase II).

PloS one Dec 27, 2024
BACKGROUND: Exposure of critically ill patients to antibiotics lead to intestinal dysbiosis, which often manifests as antibiotic-associated diarrhoea. Faecal microbiota transplantation restores gut microbiota and may lead to faster resolution of diar...
Diarrhea Feces Gastrointestinal Microbiome Fecal Microbiota Transplantation Critical Illness Female Male Humans Dysbiosis Anti-Bacterial Agents Multicenter Studies as Topic Prospective Studies Randomized Controlled Trials as Topic Clinical Trials, Phase II as Topic
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Detecting irregularities in randomized controlled trials using machine learning.

Clinical trials (London, England) Nov 25, 2024
BACKGROUND: Over the course of a clinical trial, irregularities may arise in the data. Trialists implement human-intensive, expensive central statistical monitoring procedures to identify and correct these irregularities before the results of the tri...
Randomized Controlled Trials as Topic Data Interpretation, Statistical Machine Learning Algorithms Multicenter Studies as Topic Humans
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Exploring Heterogeneity in the Cost-Effectiveness of High-Flow Nasal Cannula Therapy in Acutely Ill Children-Insights From the Step-Up First-line Support for Assistance in Breathing in Children Trial Using a Machine Learning Method.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research Sep 28, 2024
OBJECTIVES: To investigate heterogeneity in the cost-effectiveness of high-flow nasal cannula (HFNC) therapy compared with continuous positive airway pressure (CPAP) for acutely ill children requiring noninvasive respiratory support.
Humans Machine Learning Cost-Benefit Analysis Female Quality-Adjusted Life Years United Kingdom Infant, Newborn Oxygen Inhalation Therapy Intensive Care Units, Pediatric Male Continuous Positive Airway Pressure Multicenter Studies as Topic Equivalence Trials as Topic Infant Adolescent Randomized Controlled Trials as Topic Cannula Child, Preschool Acute Disease Child
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Comment on "Utilizing deep learning for automated detection of oral lesions: A multicenter study".

Oral oncology Jul 4, 2024
Mouth Neoplasms Humans Deep Learning Multicenter Studies as Topic
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Assessing the effectiveness of artificial intelligence (AI) in prioritising CT head interpretation: study protocol for a stepped-wedge cluster randomised trial (ACCEPT-AI).

BMJ open Jun 16, 2024
INTRODUCTION: Diagnostic imaging is vital in emergency departments (EDs). Accessibility and reporting impacts ED workflow and patient care. With radiology workforce shortages, reporting capacity is limited, leading to image interpretation delays. Tur...
Head Humans Multicenter Studies as Topic Artificial Intelligence Randomized Controlled Trials as Topic Algorithms Emergency Service, Hospital Tomography, X-Ray Computed
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