Microinvasive adenocarcinoma (MIA) and invasive adenocarcinoma (IAC) require distinct treatment strategies and are associated with different prognoses, underscoring the importance of accurate differentiation. This study aims to develop a predictive m...
Primary liver cancer is the sixth most commonly diagnosed cancer globally and the third leading cause of cancer-related deaths. Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, and microvascular invasion (MVI) is a sign...
The intrinsic complexity of biological processes often hides the role of dynamic microenvironmental cues in the development of pathological states. Microphysiological systems (MPSs) are emerging technological platforms that model dynamics of tissue-...
To develop and validate artificial intelligence models based on contrast-enhanced CT(CECT) images of venous phase using deep learning (DL) and Radiomics approaches to predict lymphovascular invasion in gastric cancer prior to surgery. We retrospectiv...
PURPOSE: In the context of precision medicine, radiomics has become a key technology in solving medical problems. For adenocarcinoma of esophagogastric junction (AEG), developing a preoperative CT-based prediction model for AEG invasion and lymph nod...
Medical oncology (Northwood, London, England)
Jun 26, 2025
Perineural invasion (PNI) refers to the infiltration of tumor cells into the connective tissue of nerves and is increasingly recognized as a pathological hallmark of multiple cancers, including pancreatic, prostate, colorectal, breast, and head and n...
OBJECTIVE: To develop and validate a machine learning framework combined with a nomogram for predicting recurrence after radical gastrectomy in patients with vascular and neural invasion.
International journal of colorectal disease
May 27, 2025
PURPOSE: The purpose is to evaluate the predictive value of dual-energy CT (DECT) combined with histogram parameters and a clinical prediction model for perineural invasion (PNI) in colorectal cancer (CRC).
BACKGROUND: Accurate preoperative evaluation of cT1N0M0 papillary thyroid carcinoma (PTC) is essential for guiding appropriate treatment strategies. Although ultrasound is widely used for clinical staging, it has limitations in detecting lymph node m...
Tumor budding (TB) and poorly differentiated clusters (PDCs) are features of infiltrative growth patterns and powerful independent prognostic factors in colorectal cancer (CRC), yet the underlying biological mechanisms behind their role in CRC invasi...
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