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Neovascularization, Pathologic

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Automatic detection of neovascularization on optic disk region with feature extraction and support vector machine.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Neovascularization (NV) is a definitive indicator for the onset of Proliferative Diabetic Retinopathy (PDR). The new vessels are fragile and prone to bleed, leading to high risk of sudden vision loss. Automatic detection of NV is an important task in...

Monitoring vascular normalization induced by antiangiogenic treatment with (18)F-fluoromisonidazole-PET.

Molecular oncology
BACKGROUND: Rationalization of antiangiogenics requires biomarkers. Vascular re-normalization is one widely accepted mechanism of action for this drug class. The interstitium of tumors with abnormal vasculature is hypoxic. We sought to track vascular...

Deep Learning for Drug Discovery and Cancer Research: Automated Analysis of Vascularization Images.

IEEE/ACM transactions on computational biology and bioinformatics
Likely drug candidates which are identified in traditional pre-clinical drug screens often fail in patient trials, increasing the societal burden of drug discovery. A major contributing factor to this phenomenon is the failure of traditional in vitro...

Machine Learning Based Automatic Neovascularization Detection on Optic Disc Region.

IEEE journal of biomedical and health informatics
In this paper, the automatic detection of neovascularization in the optic disc region (NVD) for color fundus retinal image is presented. NV is the indicator for the onset of proliferative diabetic retinopathy and it is featured by the presence of new...