Biomedical physics & engineering express
Mar 13, 2025
. Polygenic risk scores (PRS) summarise genetic information into a single number with clinical and research uses. Deep learning (DL) has revolutionised multiple fields, however, the impact of DL on PRSs has been less significant. We explore how DL ca...
BACKGROUND: Early and accurate identification of epidermal growth factor receptor (EGFR) mutation status in non-small cell lung cancer (NSCLC) patients with brain metastases is critical for guiding targeted therapy. This study aimed to develop a deep...
OBJECTIVE: Early assessment and intervention of Acquired Immune Deficiency Syndrome (AIDS) patients at high risk of mortality is critical. This study aims to develop an optimally performing mortality risk prediction model for AIDS patients with comor...
Journal of infection and public health
Mar 11, 2025
BACKGROUND: Talaromyces marneffei is an emerging pathogen, and the number of infections in HIV-negative individuals is increasing. In HIV-negative individuals, talaromycosis is usually misdiagnosed as another disease, especially tuberculosis (TB).
BACKGROUND: The aim of this study was to develop and internally validate an interpretable machine learning (ML) model for predicting the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB) infection.
This study aims to construct a prediction model for the demand for medical and daily care services of the elderly and to explore the factors that affect the demand for medical and daily care services of the elderly. In this study, a questionnaire sur...
Frontiers in cellular and infection microbiology
Mar 11, 2025
BACKGROUND: Although highly active antiretroviral therapy (HAART) has greatly enhanced the prognosis for people living with HIV (PLWH), some individuals fail to achieve adequate immune reconstitution, known as immunological nonresponse (INR), which i...
OBJECTIVE: This study aimed to construct a model based on machine learning to predict new HIV infections in HIV-negative men who have sex with men (MSM).
BACKGROUND: Dementia is a multifaceted disorder that affects cognitive function, necessitating accurate diagnosis for effective management and treatment. Although the Mini-Mental State Examination (MMSE) is widely used to assess cognitive impairment,...
International journal of medical informatics
Mar 9, 2025
BACKGROUND: Timely and accurate outcome prediction is essential for clinical decision-making for ischemic stroke patients in the intensive care unit (ICU). However, the interpretation and translation of predictive models into clinical applications ar...