AIMC Topic: Sensitivity and Specificity

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Natural Language Processing for Asthma Ascertainment in Different Practice Settings.

The journal of allergy and clinical immunology. In practice
BACKGROUND: We developed and validated NLP-PAC, a natural language processing (NLP) algorithm based on predetermined asthma criteria (PAC) for asthma ascertainment using electronic health records at Mayo Clinic.

A Machine-Learning Algorithm Toward Color Analysis for Chronic Liver Disease Classification, Employing Ultrasound Shear Wave Elastography.

Ultrasound in medicine & biology
The purpose of the present study was to employ a computer-aided diagnosis system that classifies chronic liver disease (CLD) using ultrasound shear wave elastography (SWE) imaging, with a stiffness value-clustering and machine-learning algorithm. A c...

KAPS (kinematic assessment of passive stretch): a tool to assess elbow flexor and extensor spasticity after stroke using a robotic exoskeleton.

Journal of neuroengineering and rehabilitation
BACKGROUND: Spasticity is a common sequela of stroke. Traditional assessment methods include relatively coarse scales that may not capture all characteristics of elevated muscle tone. Thus, the aim of this study was to develop a tool to quantitativel...

Fully automatic detection of lung nodules in CT images using a hybrid feature set.

Medical physics
PURPOSE: The aim of this study was to develop a novel technique for lung nodule detection using an optimized feature set. This feature set has been achieved after rigorous experimentation, which has helped in reducing the false positives significantl...

An Advanced Deep Learning Approach for Ki-67 Stained Hotspot Detection and Proliferation Rate Scoring for Prognostic Evaluation of Breast Cancer.

Scientific reports
Being a non-histone protein, Ki-67 is one of the essential biomarkers for the immunohistochemical assessment of proliferation rate in breast cancer screening and grading. The Ki-67 signature is always sensitive to radiotherapy and chemotherapy. Due t...

Unsupervised Learning of Spike Patterns for Seizure Detection and Wavefront Estimation of High Resolution Micro Electrocorticographic ( $\mu $ ECoG) Data.

IEEE transactions on nanobioscience
For the past few years, we have developed flexible, active, and multiplexed recording devices for high resolution recording over large, clinically relevant areas in the brain. While this technology has enabled a much higher-resolution view of the ele...

Premature ventricular contraction detection combining deep neural networks and rules inference.

Artificial intelligence in medicine
Premature ventricular contraction (PVC), which is a common form of cardiac arrhythmia caused by ectopic heartbeat, can lead to life-threatening cardiac conditions. Computer-aided PVC detection is of considerable importance in medical centers or outpa...

Laboratory parameter-based machine learning model for excluding non-alcoholic fatty liver disease (NAFLD) in the general population.

Alimentary pharmacology & therapeutics
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) affects 20%-40% of the general population in developed countries and is an increasingly important cause of hepatocellular carcinoma. Electronic medical records facilitate large-scale epidemiologic...

Automated analysis of brain activity for seizure detection in zebrafish models of epilepsy.

Journal of neuroscience methods
BACKGROUND: Epilepsy is a chronic neurological condition, with over 30% of cases unresponsive to treatment. Zebrafish larvae show great potential to serve as an animal model of epilepsy in drug discovery. Thanks to their high fecundity and relatively...