AIMC Topic: Serologic Tests

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Serologic biomarker discovery for differentiating Lyme disease from diseases with similar clinical symptoms using broad profiling of antibody binding.

Frontiers in immunology May 16, 2025
INTRODUCTION: Lyme disease (LD) is a tick-borne disease that is a substantial public health burden with estimated about 0.5 million new cases per year in the US and increasing incidence. Differentiating Lyme disease, especially in its early stages, f...
Humans Machine Learning Biomarkers Diagnosis, Differential Lyme Disease Serologic Tests Antibodies, Bacterial Borrelia burgdorferi Female Adult Male Middle Aged
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Development of a diagnostic model for biliary atresia based on MMP7 and serological tests using machine learning.

Pediatric surgery international Jul 19, 2024
OBJECTIVE: To develop a machine learning diagnostic model based on MMP7 and other serological testing indicators for early and efficient diagnosis of biliary atresia (BA).
Matrix Metalloproteinase 7 Biliary Atresia Infant, Newborn Infant Feces Serologic Tests Humans Machine Learning Retrospective Studies
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A Paper-Based Multiplexed Serological Test to Monitor Immunity against SARS-COV-2 Using Machine Learning.

ACS nano Jun 18, 2024
The rapid spread of SARS-CoV-2 caused the COVID-19 pandemic and accelerated vaccine development to prevent the spread of the virus and control the disease. Given the sustained high infectivity and evolution of SARS-CoV-2, there is an ongoing interest...
SARS-CoV-2 Humans Immunoglobulin M Machine Learning Antibodies, Viral COVID-19 Serological Testing COVID-19 Paper Immunoglobulin G Serologic Tests
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A collaborative robotic solution to partly automate SARS-CoV-2 serological tests in small facilities.

SLAS technology Oct 25, 2021
The outbreak of COVID-19 has introduced a significant stress on the healthcare systems of many countries. The availability of quick and reliable screening methodologies can be regarded as the keystone approach to mitigate the spread of the infection ...
Humans Serologic Tests COVID-19 SARS-CoV-2 Mass Screening Robotics
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High-dimensional hepatopath data analysis by machine learning for predicting HBV-related fibrosis.

Scientific reports Mar 3, 2021
Chronic HBV infection, the main cause of liver cirrhosis and hepatocellular carcinoma, has become a global health concern. Machine learning algorithms are particularly adept at analyzing medical phenomenon by capturing complex and nonlinear relations...
Male Middle Aged China ROC Curve Hepatitis B virus Forecasting Female Aged Adult Biopsy Hepatitis B, Chronic Serologic Tests Data Accuracy Genotype Liver Cirrhosis Models, Statistical Bayes Theorem Humans Machine Learning Data Analysis
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Domain-Scan: Combinatorial Sero-Diagnosis of Infectious Diseases Using Machine Learning.

Frontiers in immunology Feb 10, 2021
The presence of pathogen-specific antibodies in an individual's blood-sample is used as an indication of previous exposure and infection to that specific pathogen (e.g., virus or bacterium). Measurement of the diagnostic antibodies is routinely achie...
HIV Antibodies AIDS Serodiagnosis Antigen-Antibody Reactions DNA, Recombinant HIV Envelope Protein gp160 Hepatitis C Antigens Base Sequence Polymerase Chain Reaction Hepatitis C Antibodies HIV Core Protein p24 Genetic Vectors Hepatitis C Serologic Tests High-Throughput Nucleotide Sequencing DNA Barcoding, Taxonomic Humans Machine Learning Communicable Diseases HIV Infections Peptide Library Peptide Fragments Epitopes Amino Acid Sequence Oligonucleotides
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Artificial neural networks help to identify disease subsets and to predict lymphoma in primary Sjögren's syndrome.

Clinical and experimental rheumatology Aug 14, 2018
OBJECTIVES: Primary Sjögren's syndrome (pSS) is a complex chronic systemic disorder, for which specific and effective therapeutic interventions are still lacking. In this era of precision medicine, there is a clear need for a better definition of dis...
Prognosis Female Reproducibility of Results Risk Factors Aged Male Middle Aged Disease Progression Severity of Illness Index Humans Neural Networks, Computer Decision Support Techniques Principal Component Analysis Phenotype Biomarkers Autoantibodies Diagnosis, Computer-Assisted Data Mining Lymphoma Serologic Tests Diagnosis, Differential Sjogren's Syndrome Predictive Value of Tests
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Predictive factors of spontaneous CMV DNAemia clearance in kidney transplantation.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Dec 29, 2017
UNLABELLED: Cytomegalovirus (CMV) infection occurs frequently after solid organ transplantation. Therapeutic strategies, in particular when to start a curative treatment, has not yet been defined. The purpose of this study was to assess predictive fa...
Cytomegalovirus Cytomegalovirus Infections Serologic Tests Polymerase Chain Reaction Antibiotic Prophylaxis Antiviral Agents Tissue Donors DNA, Viral Follow-Up Studies Female Valganciclovir Humans Aged Kidney Transplantation Male Prospective Studies Middle Aged Retrospective Studies ROC Curve
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Development of a plasminogen activator inhibitor (PAI-1) assay and comparison of plasma PAI-1 activity in hyperlipidemic/dyslipidemic dogs with either hyperadrenocorticism or diabetes mellitus, and healthy dogs.

Research in veterinary science Nov 8, 2016
Thrombosis is a serious complication of many canine diseases and may be related to decreased fibrinolytic potential. Plasminogen activator inhibitor-1 (PAI-1) is the key regulator of fibrinolysis with increased levels demonstrated in states of pro-th...
Animals Plasminogen Activator Inhibitor 1 Male Hyperlipidemias Humans Diabetes Mellitus Serologic Tests Female Dogs Adrenocortical Hyperfunction Sensitivity and Specificity Dog Diseases
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[Virological evolution of patients with HIV infection that start antiretroviral therapy with a very high baseline viral load].

Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia Dec 1, 2021
BACKGROUND: The degree of viral suppression in HIV patients who start antiretroviral therapy (ART) with very high viral loads (CV) is unknown.
Humans Anti-HIV Agents Retrospective Studies CD4 Lymphocyte Count HIV Infections Antiretroviral Therapy, Highly Active Viral Load Serologic Tests
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