AIMC Topic: Treatment Outcome

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Efficacy and safety of first-line CDK4/6 inhibitors plus AI therapy for patients with HR +/HER2- advanced breast cancer: a network meta-analysis.

BMC cancer May 8, 2025
BACKGROUND: CDK4/6 inhibitors plus aromatase inhibitors (AI) significantly improve the therapeutic effect of initial treatment for HR + /HER2- advanced breast cancer. However, there is a lack of head-to-head randomized controlled trials involving the...
Benzimidazoles Randomized Controlled Trials as Topic Cyclin-Dependent Kinase 6 Receptors, Estrogen Progression-Free Survival Purines Network Meta-Analysis as Topic Receptor, ErbB-2 Receptors, Progesterone Aminopyridines Aromatase Inhibitors Cyclin-Dependent Kinase 4 Protein Kinase Inhibitors Humans Female Breast Neoplasms Antineoplastic Combined Chemotherapy Protocols Treatment Outcome
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Step up to triple therapy versus switch to dual bronchodilator therapy in patients with COPD on an inhaled corticosteroid/long-acting β-agonist: post-hoc analyses of KRONOS.

Respiratory research May 8, 2025
BACKGROUND: In people with chronic obstructive pulmonary disease (COPD) on inhaled corticosteroid/long-acting β-agonist (ICS/LABA) therapy, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommends stepping up to ICS/long-acting mu...
Drug Combinations Double-Blind Method Drug Therapy, Combination Humans Drug Substitution Adrenal Cortex Hormones Female Aged Muscarinic Antagonists Administration, Inhalation Pulmonary Disease, Chronic Obstructive Bronchodilator Agents Male Adrenergic beta-2 Receptor Agonists Middle Aged Treatment Outcome
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Radiomic analysis based on machine learning of multi-sequences MR to assess early treatment response in locally advanced nasopharyngeal carcinoma.

Science progress May 8, 2025
ObjectiveThe prediction of early response in locally advanced nasopharyngeal carcinoma (LA-NPC) after concurrent chemoradiotherapy (CCRT) is important for determining the need for timely consolidation therapy. We developed a radiomic analysis of mult...
Humans Machine Learning Algorithms Retrospective Studies Female Nasopharyngeal Carcinoma Aged Nasopharyngeal Neoplasms Middle Aged Adult ROC Curve Radiomics Treatment Outcome Male Magnetic Resonance Imaging Chemoradiotherapy
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Predicting the outcome of psychological treatments for borderline personality disorder and posttraumatic stress disorder: a machine learning approach to predict long-term outcome of Narrative Exposure Therapy vs. Dialectical Behavioral Therapy based treatment.

European journal of psychotraumatology May 7, 2025
: A comorbidity between Borderline Personality Disorder (BPD) and Posttraumatic Stress Disorder (PTSD) is common, severely disabling, and hard to treat. The choice of an optimal psychotherapy based on patient characteristics remains challenging. This...
Borderline Personality Disorder Implosive Therapy Dialectical Behavior Therapy Narrative Therapy Adult Male Middle Aged Stress Disorders, Post-Traumatic Treatment Outcome Humans Machine Learning Female
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Uncovering key factors in weight loss effectiveness through machine learning.

International journal of obesity (2005) May 6, 2025
BACKGROUND/OBJECTIVES: One of the main challenges in weight loss is the dramatic interindividual variability in response to treatment. We aim to systematically identify factors relevant to weight loss effectiveness using machine learning (ML).
Boosting Machine Learning Algorithms Weight Reduction Programs Adult Male Humans Treatment Outcome Middle Aged Machine Learning Body Mass Index Exercise Female Obesity Weight Loss Motivation Cognitive Behavioral Therapy
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Effects of exoskeleton rehabilitation robot training on neuroplasticity and lower limb motor function in patients with stroke.

BMC neurology May 3, 2025
BACKGROUND: Lower limb exoskeleton rehabilitation robot is a new technology to improve the lower limb motor function of stroke patients. Recovery of motor function after stroke is closely related to neuroplasticity in the motor cortex and associated ...
Recovery of Function Robotics Electromyography Stroke Walking Middle Aged Adolescent Treatment Outcome Neuronal Plasticity Lower Extremity Exoskeleton Device Stroke Rehabilitation Transcranial Magnetic Stimulation Humans Female Aged Young Adult Adult Male
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A deep learning-based clinical-radiomics model predicting the treatment response of immune checkpoint inhibitors (ICIs)-based conversion therapy in potentially convertible hepatocelluar carcinoma patients: a tumor marker prognostic study.

International journal of surgery (London, England) May 1, 2025
BACKGROUND: The majority of patients with hepatocellular carcinoma (HCC) miss the opportunity of radical resection, making immune check-point inhibitors (ICIs)-based conversion therapy a primary option. However, challenges persist in predicting respo...
Tomography, X-Ray Computed Female Aged Radiomics Biomarkers, Tumor Humans Prognosis Immune Checkpoint Inhibitors Male Treatment Outcome Middle Aged Deep Learning Liver Neoplasms Carcinoma, Hepatocellular
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Artificial intelligence-assisted left ventricular global longitudinal strain assessment in patients with acute myocardial infarction: a RESUS-AMI trial sub-analysis.

The international journal of cardiovascular imaging Apr 29, 2025
PURPOSE: The aim of this sub-analysis of the RESUS-AMI trial was to evaluate the correlation of artificial intelligence (AI)-assisted echocardiographic global longitudinal strain (GLS) assessments with infarct size, left ventricular ejection fraction...
Reproducibility of Results Aged Male Ventricular Function, Left Stroke Volume Percutaneous Coronary Intervention Humans Echocardiography Image Interpretation, Computer-Assisted Artificial Intelligence Magnetic Resonance Imaging, Cine Middle Aged Female Observer Variation Myocardial Contraction Treatment Outcome Global Longitudinal Strain Predictive Value of Tests ST Elevation Myocardial Infarction
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Development and validation a radiomics combined clinical model predicts treatment response for esophageal squamous cell carcinoma patients.

BMC gastroenterology Apr 29, 2025
PURPOSE: This study is aimed to develop and validate a machine learning model, which combined radiomics and clinical characteristics to predicting the definitive chemoradiotherapy (dCRT) treatment response in esophageal squamous cell carcinoma (ESCC)...
Chemoradiotherapy Esophageal Squamous Cell Carcinoma Tomography, X-Ray Computed Nomograms Female Middle Aged Humans Treatment Outcome Aged ROC Curve Machine Learning Radiomics Esophageal Neoplasms Logistic Models Retrospective Studies Male
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Flexor Synergy Assessment and Therapy for Persons With Stroke Using the ULIX Low Impedance Robot.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society Apr 29, 2025
The flexor synergy after stroke results in involuntary activation of distal muscles when lifting the shoulder against gravity. This contributes to impaired ability to perform activities of daily living. Robotic exoskeletons can be useful in assessing...
Stroke Rehabilitation Electromyography Stroke Range of Motion, Articular Electric Impedance Exoskeleton Device Middle Aged Treatment Outcome Muscle, Skeletal Robotics Female Equipment Design Aged Adult Biomechanical Phenomena Humans Male
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