AIMC Topic: Aged, 80 and over

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Inferring protein expression changes from mRNA in Alzheimer's dementia using deep neural networks.

Nature communications
Identifying the molecular systems and proteins that modify the progression of Alzheimer's disease and related dementias (ADRD) is central to drug target selection. However, discordance between mRNA and protein abundance, and the scarcity of proteomic...

Propofol Anesthesia Depth Monitoring Based on Self-Attention and Residual Structure Convolutional Neural Network.

Computational and mathematical methods in medicine
METHODS: We compare nine index values, select CNN+EEG, which has good correlation with BIS index, as an anesthesia state observation index to identify the parameters of the model, and establish a model based on self-attention and dual resistructure c...

Multiple instance learning detects peripheral arterial disease from high-resolution color fundus photography.

Scientific reports
Peripheral arterial disease (PAD) is caused by atherosclerosis and is a common disease of the elderly leading to excess morbidity and mortality. Early PAD diagnosis is important, as the only available causal therapy is addressing risk factors like sm...

DNA Methylation Biomarkers-Based Human Age Prediction Using Machine Learning.

Computational intelligence and neuroscience
PURPOSE: Age can be an important clue in uncovering the identity of persons that left biological evidence at crime scenes. With the availability of DNA methylation data, several age prediction models are developed by using statistical and machine lea...

Efficacy and feasibility of robot-assisted partial nephrectomy for octogenarians: comparison with younger counterparts.

Journal of robotic surgery
To compare short-term functional and surgical outcomes of robot-assisted partial nephrectomy (RAPN) in patients ≥ 80 years old and their younger counterparts, we retrospectively analyzed 1234 patients who underwent robot-assisted partial nephrectomy....

Machine learning assisted real-time deformability cytometry of CD34+ cells allows to identify patients with myelodysplastic syndromes.

Scientific reports
Diagnosis of myelodysplastic syndrome (MDS) mainly relies on a manual assessment of the peripheral blood and bone marrow cell morphology. The WHO guidelines suggest a visual screening of 200 to 500 cells which inevitably turns the assessor blind to r...

Prediction model of acute kidney injury induced by cisplatin in older adults using a machine learning algorithm.

PloS one
BACKGROUND: Early detection and prediction of cisplatin-induced acute kidney injury (Cis-AKI) are essential for the management of patients on chemotherapy with cisplatin. This study aimed to evaluate the performance of a prediction model for Cis-AKI.

Deep learning-based algorithm for lung cancer detection on chest radiographs using the segmentation method.

Scientific reports
We developed and validated a deep learning (DL)-based model using the segmentation method and assessed its ability to detect lung cancer on chest radiographs. Chest radiographs for use as a training dataset and a test dataset were collected separatel...

Machine learning prediction model of acute kidney injury after percutaneous coronary intervention.

Scientific reports
Acute kidney injury (AKI) after percutaneous coronary intervention (PCI) is associated with a significant risk of morbidity and mortality. The traditional risk model provided by the National Cardiovascular Data Registry (NCDR) is useful for predictin...