White matter hyperintensity (WMH) is a primary manifestation of small vessel disease (SVD), leading to vascular cognitive impairment and other disorders. Accurate WMH quantification is vital for diagnosis and prognosis, but current automatic segmenta...
Clinica chimica acta; international journal of clinical chemistry
Jul 15, 2025
Urothelial carcinoma (UC) is a highly malignant disease with significant public health implications. Despite advancements in oncology, early diagnosis and effective prognostic tools remain limited. This study aimed to develop a machine learning model...
BACKGROUND: Transformer-based neural networks excel in modelling high-dimensional, time-series data with complex dependencies. This proof-of-concept study applies a transformer-X-learner framework to estimate treatment effects using real-world data, ...
BACKGROUND: The combination of antidepressant and antipsychotic medication is an effective treatment for major depressive disorder with psychotic features ('psychotic depression'). The present study aims to identify sociodemographic and clinical pred...
Accurate identification of clinically malignant pleural effusions is critical for cancer diagnosis and subsequent treatment planning. Here, surface-enhanced Raman spectroscopy (SERS) data of pleural effusions and serum carcinoembryonic antigen (CEA) ...
Allogeneic hematopoietic cell transplantation (allo-HCT) is potentially curative for older adults with hematologic malignancies. Concerns on nonrelapse mortality (NRM) in older adults limit allo-HCT utilization. We executed a prospective, observation...
The advent of endovascular thrombectomy has significantly improved outcomes for stroke patients with intracranial large vessel occlusion, yet individual benefits can vary widely. As demand for thrombectomy rises and geographical disparities in stroke...
Nerve conduction F-wave studies contain crucial information about subclinical motor dysfunction that can be used to diagnose patients with amyotrophic lateral sclerosis (ALS). However, F-wave responses are highly variable in morphology, making wavefo...
Ensuring the high quality of colonoscopies in colorectal cancer (CRC) screening is essential to reducing CRC. Recently, computer-aided detection systems (CADe) that use artificial intelligence have attracted much attention as potentially useful tools...
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms, including cognitive impairment. Its diagnosis, which used to be based on clinical assessment, increasingly relies on biomarkers. While electroence...
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