Amphetamine has widespread effects on multiple neurotransmitter systems, potentially altering the physiological connectivity and network dynamics across various regions of the brain. In this study, we investigated the effects of D-amphetamine using o...
Male infertility affects a significant portion of couples worldwide, with standard semen analysis often failing to identify functional deficiencies in sperm performance. This study presents a microfluidic platform for characterizing sperm flagellar b...
Heterogeneity in cancer is known to be a contributor to the formation of metastatic lesions, poor prognosis, and ultimately undermines therapeutic efficacy. This same tumor heterogeneity is reflected in circulating tumor cells (CTCs) and tumor derive...
Antimicrobial resistance (AMR) in enterica serotype Kentucky ( Kentucky) is a global challenge, with increasing resistance to cephalosporins, ciprofloxacin, and carbapenems significantly limiting treatment strategies, yet its worldwide dissemination...
Proceedings of the National Academy of Sciences of the United States of America
Nov 3, 2025
Self-assembling protein nanoparticles are being increasingly utilized in the design of next-generation vaccines due to their ability to induce antibody responses of superior magnitude, breadth, and durability. Computational protein design offers a ro...
Red Palm Weevil(RPW) infestation is a major challenge in palm production, often remaining undetected until severe internal damage has occurred. This proposed work presents a novel non-invasive auditory detection system that combines advanced signal p...
Hyperspectral imaging (HSI) has emerged as a powerful non-destructive technique for evaluating fresh meat quality across multiple attributes simultaneously. This review critically examines recent advances in HSI applications for fresh beef, pork, and...
Proceedings of the National Academy of Sciences of the United States of America
Oct 31, 2025
Memory consolidation refers to a process of engram reorganization and stabilization that is thought to occur primarily during sleep through a combination of neural replay, homeostatic plasticity, synaptic maturation, and pruning. From a computational...
Bone fracture continues to pose a significant clinical challenge in regenerative medicine due to limited repair capacity and inadequate therapeutic options. Among the various therapeutic strategies, mesenchymal stem cells have shown strong potential ...
(Z)-endoxifen (endoxifen) is the active metabolite of tamoxifen. Endoxifen is a potent antiestrogen that binds and blocks estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ). Early-phase clinical trials have shown that endoxifen has promis...
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