OBJECTIVE: The lack of a rapid, validated, consistent test for tracking disease activity in patients with inflammatory bowel disease (IBD) is currently a major challenge. Currently used biomarkers have notable disadvantages, such as the slow processi...
Diabetic foot ulcers (DFUs) are a severe complication of diabetes, characterized by impaired wound healing, chronic inflammation, and tissue degradation. N-methyladenosine (mA), has emerged as a critical regulator in gene expression and cellular func...
Type A aortic dissection (TAAD) is a vascular disease with high mortality; however, the role of gene methylation in its pathogenesis has received little attention. This study aimed to identify candidate markers of TAAD by integrating methylation and ...
This study explores the relationship between inflammatory biomarkers and the risk of endometriosis, aiming to develop a predictive model using National Health and Nutrition Examination Survey (1999-2006) data. The dataset included 4,089 females with ...
Analytical methods : advancing methods and applications
Nov 27, 2025
Cellular surface receptors are commonly used as diagnostic and prognostic biomarkers for many infectious diseases. Benchtop clinical instruments, , flow cytometers and fluorescence microscopes are commonly employed for identification and quantificati...
BACKGROUND: Hepatic ischemia-reperfusion injury (HIRI) represents the leading cause of postoperative liver dysfunction and failure. Ammonia-induced cell death (ACD), defined by lysosomal and mitochondrial disruption due to intracellular ammonia accum...
BACKGROUND: Numerous studies have manifested that cellular senescence involves in the pathogenesis of intervertebral disc degeneration (IDD). Here, we constructed a novel senescence-related genes (SRGs) signature for IDD.
BACKGROUND: Lipids play a vital role in health and disease, but changes to their circulating levels and the link with schizophrenia remains poorly characterized. This study aimed to investigate the pathological lipid profiles in patients with first-e...
BACKGROUND: Diabetic kidney disease (DKD) remains a leading cause of chronic kidney disease worldwide. However, current diagnostic methods rely on indirect biomarkers or invasive renal biopsy. This study aimed to evaluate the feasibility of urinary v...
Keratoconus (KC) is a progressive corneal disorder characterized by thinning of the cornea and conical protrusion leading to distorted vision and blindness. The disease often marks in adolescence and progresses until the mid-40s, with varying degrees...
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