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Case-Control Studies

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Prognostic Biomarkers for Thrombotic Microangiopathy after Acute Graft-versus-Host Disease: A Nested Case-Control Study.

Transplantation and cellular therapy
Transplantation-associated thrombotic microangiopathy (TA-TMA) is a complication of allogeneic hematopoietic cell transplantation (HCT) that often occurs following the development of acute graft-versus-host disease (aGVHD). In this study, we aimed to...

Using supervised machine learning on neuropsychological data to distinguish OCD patients with and without sensory phenomena from healthy controls.

The British journal of clinical psychology
OBJECTIVES: While theoretical models link obsessive-compulsive disorder (OCD) with executive function deficits, empirical findings from the neuropsychological literature remain mixed. These inconsistencies are likely exacerbated by the challenge of h...

Image-Based Machine Learning Algorithms for Disease Characterization in the Human Type 1 Diabetes Pancreas.

The American journal of pathology
Emerging data suggest that type 1 diabetes affects not only the β-cell-containing islets of Langerhans, but also the surrounding exocrine compartment. Using digital pathology, machine learning algorithms were applied to high-resolution, whole-slide i...

Training confounder-free deep learning models for medical applications.

Nature communications
The presence of confounding effects (or biases) is one of the most critical challenges in using deep learning to advance discovery in medical imaging studies. Confounders affect the relationship between input data (e.g., brain MRIs) and output variab...

Bone Mineral Density and Content Among Patients With Coronary Artery Disease: A Comparative Study.

The American journal of the medical sciences
INTRODUCTION: Some studies indicate an association between coronary artery disease (CAD) and osteoporosis. This case-control study examined the association between body composition and bone mineral content (BMC) and density (BMD) among patients with ...

Broad Learning Enhanced H-MRS for Early Diagnosis of Neuropsychiatric Systemic Lupus Erythematosus.

Computational and mathematical methods in medicine
In this paper, we explore the potential of using the multivoxel proton magnetic resonance spectroscopy (H-MRS) to diagnose neuropsychiatric systemic lupus erythematosus (NPSLE) with the assistance of a support vector machine broad learning system (BL...

Computer-aided diagnosis of pectus excavatum using CT images and deep learning methods.

Scientific reports
Pectus excavatum (PE) is one of the most common chest wall defects. Accurate assessment of PE deformities is critical for effective surgical intervention. Index-based evaluations have become the standard for objectively estimating PE, however, these ...

Automated estimation of echocardiogram image quality in hospitalized patients.

The international journal of cardiovascular imaging
We developed a machine learning model for efficient analysis of echocardiographic image quality in hospitalized patients. This study applied a machine learning model for automated transthoracic echo (TTE) image quality scoring in three inpatient grou...

Artificial intelligence for the detection of vertebral fractures on plain spinal radiography.

Scientific reports
Vertebral fractures (VFs) cause serious problems, such as substantial functional loss and a high mortality rate, and a delayed diagnosis may further worsen the prognosis. Plain thoracolumbar radiography (PTLR) is an essential method for the evaluatio...