AIMC Topic: Computational Biology

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Database Mining of Genes of Prognostic Value for the Prostate Adenocarcinoma Microenvironment Using the Cancer Gene Atlas.

BioMed research international
BACKGROUND: Prostate adenocarcinoma (PRAD) is a common malignant tumor in elderly men. Our research uses The Cancer Gene Atlas (TCGA) database to find potential related genes for predicting the prognosis of patients with PRAD.

Interpretable Learning Approaches in Resting-State Functional Connectivity Analysis: The Case of Autism Spectrum Disorder.

Computational and mathematical methods in medicine
Deep neural networks have recently been applied to the study of brain disorders such as autism spectrum disorder (ASD) with great success. However, the internal logics of these networks are difficult to interpret, especially with regard to how specif...

EEG Signal and Feature Interaction Modeling-Based Eye Behavior Prediction Research.

Computational and mathematical methods in medicine
In recent years, with the development of brain science and biomedical engineering, as well as the rapid development of electroencephalogram (EEG) signal analysis methods, using EEG signals to monitor human health has become a very popular research fi...

AxoNet: A deep learning-based tool to count retinal ganglion cell axons.

Scientific reports
In this work, we develop a robust, extensible tool to automatically and accurately count retinal ganglion cell axons in optic nerve (ON) tissue images from various animal models of glaucoma. We adapted deep learning to regress pixelwise axon count de...

3D-MCN: A 3D Multi-scale Capsule Network for Lung Nodule Malignancy Prediction.

Scientific reports
Despite the advances in automatic lung cancer malignancy prediction, achieving high accuracy remains challenging. Existing solutions are mostly based on Convolutional Neural Networks (CNNs), which require a large amount of training data. Most of the ...

CNN-Peaks: ChIP-Seq peak detection pipeline using convolutional neural networks that imitate human visual inspection.

Scientific reports
ChIP-seq is one of the core experimental resources available to understand genome-wide epigenetic interactions and identify the functional elements associated with diseases. The analysis of ChIP-seq data is important but poses a difficult computation...

iMethyl-Deep: N6 Methyladenosine Identification of Yeast Genome with Automatic Feature Extraction Technique by Using Deep Learning Algorithm.

Genes
One of the most common and well studied post-transcription modifications in RNAs is N6-methyladenosine (m6A) which has been involved with a wide range of biological processes. Over the past decades, N6-methyladenosine produced some positive consequen...

An Application of Random Walk Resampling to Phylogenetic HMM Inference and Learning.

IEEE transactions on nanobioscience
Statistical resampling methods are widely used for confidence interval placement and as a data perturbation technique for statistical inference and learning. An important assumption of popular resampling methods such as the standard bootstrap is that...

Cross-Subject Seizure Detection in EEGs Using Deep Transfer Learning.

Computational and mathematical methods in medicine
Electroencephalography (EEG) plays an import role in monitoring the brain activities of patients with epilepsy and has been extensively used to diagnose epilepsy. Clinically reading tens or even hundreds of hours of EEG recordings is very time consum...