AI Medical Compendium Topic

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Disease Models, Animal

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Neuroprotective effects of Suhexiang Wan on the in vitro and in vivo models of Parkinson's disease.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan Dec 1, 2019
OBJECTIVE: To examine the role of KSOP1009 (a modified formulation of Suhexiang Wan essential oil) in an animal model of Parkinson's disease (PD) induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) injection.
Cell Survival Cell Line, Tumor Humans Mice Parkinson Disease Brain Neuroprotective Agents Drugs, Chinese Herbal Animals Mice, Inbred ICR Disease Models, Animal Blotting, Western Male Mitochondria Reactive Oxygen Species Immunohistochemistry Substantia Nigra
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Machine Learning Approach for Predicting Past Environmental Exposures From Molecular Profiling of Post-Exposure Human Serum Samples.

Journal of occupational and environmental medicine Dec 1, 2019
OBJECTIVE: To develop an approach for a retrospective analysis of post-exposure serum samples using diverse molecular profiles.
Female Young Adult Adult Animals Male Humans Machine Learning Biomarkers Cotinine Environmental Exposure Sex Factors Smoking Tobacco Smoke Pollution Adolescent Support Vector Machine Age Factors Disease Models, Animal Mice, Inbred C57BL
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Effects of extracts from Chuanwu (Aconitum Carmichaelii) and Banxia (Rhizoma Pinelliae) on excisional wound healing in a rat's model.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan Feb 1, 2019
OBJEVTIVE: To investigate the effects of extracts from Chuanwu (Aconitum Carmichaelii) and Banxia (Rhizoma Pinelliae) on the excisional wound healing in a rat's model.
Rats Interleukin-2 Rats, Sprague-Dawley Wound Healing Interleukin-10 Disease Models, Animal Tumor Necrosis Factor-alpha Interleukin-4 Animals Real-Time Polymerase Chain Reaction Drugs, Chinese Herbal Transforming Growth Factor beta1 Aconitum Fibroblast Growth Factor 2 Pinellia
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Network Tomography for Understanding Phenotypic Presentations in Aortic Stenosis.

JACC. Cardiovascular imaging Feb 1, 2019
OBJECTIVES: This study sought to build a patient-patient similarity network using multiple features of left ventricular (LV) structure and function in patients with aortic stenosis (AS). The study further validated the observations in an experimental...
Humans Machine Learning Female Reproducibility of Results Balloon Valvuloplasty Severity of Illness Index Time Factors Male Disease Models, Animal Ventricular Function, Left Predictive Value of Tests Aortic Valve Stenosis Echocardiography Mice, Knockout Aortic Valve Middle Aged Aged Heart Ventricles Disease Progression Image Interpretation, Computer-Assisted Aged, 80 and over Heart Valve Prosthesis Implantation Cross-Sectional Studies Animals
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Ajudecumin A from Ajuga ovalifolia var. calantha exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW264.7 murine macrophages and animal models of acute inflammation.

Pharmaceutical biology Dec 1, 2018
CONTEXT: Ajuga ovalifolia Bur. et Franch. var. calantha (Diels) C. Y. Wu et C. Chen (Labiatae), a traditional Chinese medicine, has been used to treat several inflammatory diseases.
Anti-Inflammatory Agents RAW 264.7 Cells Ajuga Inflammation Disease Models, Animal Macrophages Lipopolysaccharides Animals Dose-Response Relationship, Drug Male Mice Plant Extracts
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Anti-hepatofibrosis effect of Allium senescens in activated hepatic stellate cells and thioacetamide-induced fibrosis rat model.

Pharmaceutical biology Dec 1, 2018
CONTEXT: Allium senescens Linn. (Liliaceae) (ASL) has been traditionally used in Korea and other Asian countries for improving digestive and liver functions.
Animals Male Plant Extracts Rats Liver Cirrhosis Cell Proliferation Treatment Outcome Rats, Sprague-Dawley Disease Models, Animal Cell Line Humans Cells, Cultured Cell Survival Hepatic Stellate Cells Allium Thioacetamide
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[Experimental study of a new animal model with trigeminal neuralgia produced by administration of talc to peripheral infraobital nerve in rats].

Shanghai kou qiang yi xue = Shanghai journal of stomatology Oct 1, 2018
PURPOSE: To establish a new animal model of trigeminal neuralgia（TN） produced by administration of talc to peripheral infraobital nerve in rats.
Disease Models, Animal Neuralgia Talc Trigeminal Nerve Animals Trigeminal Neuralgia Male Rats, Wistar Rats Rats, Sprague-Dawley
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Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.

World journal of gastroenterology Dec 21, 2017
AIM: To investigate whether morin can reduce hepatic fibrosis by activating the NF-E2-related factor 2 (Nrf2) signaling pathway.
Carbon Tetrachloride NF-E2-Related Factor 2 Liver Protective Agents Flavonoids Liver Function Tests Animals Male Weight Loss Oxidative Stress Antioxidants Rats Liver Cirrhosis Signal Transduction Rats, Sprague-Dawley Disease Models, Animal Humans
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[Establishment of New Zealand rabbit models of aplastic anemia].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University Dec 20, 2017
OBJECTIVE: To screen for the optimal dose of benzene and cyclophosphamide using an orthogonal design for establishment of New Zealand rabbit models of aplastic anemia.
Animals Benzene Disease Models, Animal Bone Marrow Examination Bone Marrow Anemia, Aplastic Rabbits Cyclophosphamide Blood Cell Count
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A prototype single-port device for pressurized intraperitoneal aerosol chemotherapy. Technical feasibility and local drug distribution.

Acta cirurgica brasileira Dec 1, 2017
PURPOSE: To evaluate the technical feasibility and homogeneity of drug distribution of pressurized intraperitoneal aerosol chemotherapy (PIPAC) based on a novel process of intraperitoneal drug application (multidirectional aerosolization).
Aerosols Abdominal Cavity Feasibility Studies Drug Delivery Systems Insufflation Animals Peritoneal Neoplasms Sus scrofa Time Factors Peritoneum Disease Models, Animal Pressure Injections, Intraperitoneal
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