BACKGROUND: Accurate quantification of the Ki-67 proliferation index is essential for breast cancer prognosis and treatment planning. Current automated methods, including classical and deep learning approaches based on cell detection or segmentation,...
OBJECTIVE: To develop and validate an integrated 2.5D deep learning (DL) and Radiomics model using gadoxetic acid-enhanced MRI hepatobiliary phase (HBP) images combined with clinical features for preoperative prediction of microvascular invasion (MVI...
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
Sep 27, 2025
PURPOSE: Tumors are heterogeneous and consist of subregions, also known as tumor habitats, each of which corresponds to a group of tissues with similar structural, metabolic or functional characteristics. This study aims to visualize and quantify int...
Imaging technologies and staining based pathology are important components of common practice cancer care. Specifically, H&E imaging is standard for almost all cancer patients. Traditionally, H&E images can serve, when used by experienced trained pat...
The Ki67 score is a crucial prognostic biomarker for neuroendocrine tumors, but its manual assessment is labor-intensive, requiring the counting of 500-2,000 cells in hotspots. Digital image analysis could streamline this process, yet few comprehensi...
Continuous adult hippocampal neurogenesis is involved in memory formation and mood regulation but is challenging to study in humans. Difficulties finding proliferating progenitor cells called into question whether and how new neurons may be generated...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Jun 16, 2025
This study focuses on artificial intelligence-driven classification of glioma and Ki-67 leveling using T2w-FLAIR MRI, exploring the association of Ki-67 biomarkers with deep learning (DL) features through explainable artificial intelligence (XAI) and...
OBJECTIVE: PET image analysis provides tumor heterogeneity data related to neoadjuvant chemotherapy response (NACR) and metastatic risk in osteosarcoma. Ki-67 expression is used to predict metastasis. The accuracy of prediction models with image quan...
BACKGROUND: Advancements in the management of gastric cancer (GC) and innovative therapeutic approaches highlight the significance of the role of biomarkers in GC prognosis. Machine-learning (ML)-based methods can be applied to identify the most impo...
BACKGROUND: This study aimed to preoperatively predict Ki-67 proliferation levels in patients with pancreatic solid pseudopapillary neoplasm (pSPN) using radiomics features extracted from arterial phase helical CT images.
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