AIMC Topic: Longitudinal Studies

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Targeted use of growth mixture modeling: a learning perspective.

Statistics in medicine
From the statistical learning perspective, this paper shows a new direction for the use of growth mixture modeling (GMM), a method of identifying latent subpopulations that manifest heterogeneous outcome trajectories. In the proposed approach, we uti...

Predictive time-series modeling using artificial neural networks for Linac beam symmetry: an empirical study.

Annals of the New York Academy of Sciences
Over half of cancer patients receive radiotherapy (RT) as partial or full cancer treatment. Daily quality assurance (QA) of RT in cancer treatment closely monitors the performance of the medical linear accelerator (Linac) and is critical for continuo...

Making use of longitudinal information in pattern recognition.

Human brain mapping
Longitudinal designs are widely used in medical studies as a means of observing within-subject changes over time in groups of subjects, thereby aiming to improve sensitivity for detecting disease effects. Paralleling an increased use of such studies ...

Longitudinal clinical score prediction in Alzheimer's disease with soft-split sparse regression based random forest.

Neurobiology of aging
Alzheimer's disease (AD) is an irreversible neurodegenerative disease and affects a large population in the world. Cognitive scores at multiple time points can be reliably used to evaluate the progression of the disease clinically. In recent studies,...

Cognitive Test Scores in UK Biobank: Data Reduction in 480,416 Participants and Longitudinal Stability in 20,346 Participants.

PloS one
UK Biobank includes 502,649 middle- and older-aged adults from the general population who have undergone detailed phenotypic assessment. The majority of participants completed tests of cognitive functioning, and on average four years later a sub-grou...

Temporally Constrained Group Sparse Learning for Longitudinal Data Analysis in Alzheimer's Disease.

IEEE transactions on bio-medical engineering
Sparse learning has been widely investigated for analysis of brain images to assist the diagnosis of Alzheimer's disease and its prodromal stage, i.e., mild cognitive impairment. However, most existing sparse learning-based studies only adopt cross-s...

High-Performance Personalized Heartbeat Classification Model for Long-Term ECG Signal.

IEEE transactions on bio-medical engineering
Long-term electrocardiogram (ECG) has become one of the important diagnostic assist methods in clinical cardiovascular domain. Long-term ECG is primarily used for the detection of various cardiovascular diseases that are caused by various cardiac arr...

Accelerated Brain Aging in Schizophrenia: A Longitudinal Pattern Recognition Study.

The American journal of psychiatry
OBJECTIVE: Despite the multitude of longitudinal neuroimaging studies that have been published, a basic question on the progressive brain loss in schizophrenia remains unaddressed: Does it reflect accelerated aging of the brain, or is it caused by a ...

A class of joint models for multivariate longitudinal measurements and a binary event.

Biometrics
Predicting binary events such as newborns with large birthweight is important for obstetricians in their attempt to reduce both maternal and fetal morbidity and mortality. Such predictions have been a challenge in obstetric practice, where longitudin...