BACKGROUND: Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications and seriously threatens the health of mothers and offspring. Neonicotinoids (NEOs) is a new class of pesticide and widely used worldwide. Prenatal NEOs ...
To achieve higher denitrification efficiency with reduced energy consumption in aerobic granular sludge (AGS) system, a systematic evaluation of the carbon and nitrogen metabolism process for AGS under different stage is essential. Herein, this study...
In the United States, people obtain water for household use from one of two sources. Public water systems, which are subject to rules and regulations under the Safe Drinking Water Act, or private sources such as domestic wells, which are not subject ...
Electrochemiluminescence (ECL)-based point-of-care testing (POCT) has the potential to facilitate the rapid identification of diseases, offering advantages such as high sensitivity, strong selectivity, and minimal background interference. However, as...
Extracellular vesicles (EVs) are promising non-invasive biomarkers for cancer diagnosis. EVs proteins play a critical role in tumor progress and metastasis. However, accurately and reliably diagnosing cancers is greatly limited by single protein mark...
BACKGROUND: Glioblastoma (GBM) is the most aggressive adult primary brain cancer, characterized by significant heterogeneity, posing challenges for patient management, treatment planning, and clinical trial stratification.
Given the growing burden of colorectal cancer (CRC) as a global health challenge, it becomes imperative to focus on strategies that can mitigate its impact. Post-treatment surveillance has emerged as essential for early detection of recurrence, signi...
International journal of molecular sciences
May 14, 2025
Cryptic sites, which are transient binding sites that emerge through protein conformational changes upon ligand binding, are valuable targets for drug discovery, particularly for allosteric modulators. However, identifying these sites remains challen...
International journal of molecular sciences
May 14, 2025
Lung adenocarcinoma (LUAD) is a leading cause of cancer-related mortality, with heme metabolism playing a critical role in tumor progression and treatment resistance. This study investigates the clinical implications of heme metabolism in LUAD, focus...
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