Clinical chemistry and laboratory medicine
Sep 25, 2025
OBJECTIVES: Machine learning (ML) models, using laboratory data, support early sepsis prediction. However, analytical bias in laboratory measurements can compromise their performance and validity in real-world settings. We aimed to evaluate how analy...
To evaluate the diagnostic value of coronary angiography-derived fractional flow reserve (FFR) and index of microcirculatory resistance (IMR) for identifying coronary functional abnormalities. This diagnostic study enrolled patients with clinically...
BACKGROUND: Relapse and drug resistance are major contributor to chemotherapy failure in diffuse large B-cell lymphoma (DLBCL). Programmed cell death (PCD), a key mechanism in tumor progression and resistance, has emerged as a promising biomarker for...
Vascular dementia (VaD), the second most common form of dementia, lacks reliable biomarkers for early diagnosis. Here, we integrated weighted gene co-expression network analysis (WGCNA) with machine learning to identify novel biomarkers and immune-me...
BACKGROUND: Pathological myopia (PM) has emerged as a leading cause of global visual impairment, early detection and precise grading of PM are crucial for timely intervention. The atrophy, traction and neovascularisation (ATN) system is applied to de...
AIM: To evaluate the impact of fluid volume fluctuations quantified with artificial intelligence in optical coherence tomography scans during the maintenance phase and visual outcomes at 12 and 24 months in a real-world, multicentre, national cohort ...
BACKGROUND: Brachycephalic dog breeds often exhibit a suite of extreme conformations linked with several severe and long-term disorders. Despite this, ownership levels of brachycephalic breeds remain high internationally, with physical appearance bei...
AIMS: The aim of this research is to diagnose polycythaemia vera (PV) disease using different machine learning (ML) algorithms with complete blood count (CBC) parameters before further investigations such as Janus kinase 2 (), erythropoietin (EPO) an...
The Journal of bone and joint surgery. American volume
Sep 17, 2025
BACKGROUND: Meniscal ramp lesions can impact knee stability, particularly when associated with anterior cruciate ligament (ACL) injuries. Although magnetic resonance imaging (MRI) is the primary diagnostic tool, its diagnostic accuracy remains subopt...
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Sep 15, 2025
Myocardial infarction (MI) is a leading cause of death worldwide and the most common precursor to heart failure, even after initial treatment. Precise evaluation of myocardial injury is crucial for assessing interventions and improving outcomes. Exte...
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