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Mapping Thrombosis Serum Markers by H-NMR Allied with Machine Learning Tools.
Molecules (Basel, Switzerland)
Dec 13, 2024
Machine learning and artificial intelligence tools were used to investigate the discriminatory potential of blood serum metabolites for thromboembolism and antiphospholipid syndrome (APS). H-NMR-based metabonomics data of the serum samples of patient...
Survival After Radical Cystectomy for Bladder Cancer: Development of a Fair Machine Learning Model.
JMIR medical informatics
Dec 13, 2024
BACKGROUND: Prediction models based on machine learning (ML) methods are being increasingly developed and adopted in health care. However, these models may be prone to bias and considered unfair if they demonstrate variable performance in population ...
Longitudinal Model Shifts of Machine Learning-Based Clinical Risk Prediction Models: Evaluation Study of Multiple Use Cases Across Different Hospitals.
Journal of medical Internet research
Dec 13, 2024
BACKGROUND: In recent years, machine learning (ML)-based models have been widely used in clinical domains to predict clinical risk events. However, in production, the performances of such models heavily rely on changes in the system and data. The dyn...
Real-World and Clinical Trial Validation of a Deep Learning Radiomic Biomarker for PD-(L)1 Immune Checkpoint Inhibitor Response in Advanced Non-Small Cell Lung Cancer.
JCO clinical cancer informatics
Dec 13, 2024
PURPOSE: This study developed and validated a novel deep learning radiomic biomarker to estimate response to immune checkpoint inhibitor (ICI) therapy in advanced non-small cell lung cancer (NSCLC) using real-world data (RWD) and clinical trial data.
A supervised machine learning statistical design of experiment approach to modeling the barriers to effective snakebite treatment in Ghana.
PLoS neglected tropical diseases
Dec 13, 2024
BACKGROUND: Snakebite envenoming is a serious condition that affects 2.5 million people and causes 81,000-138,000 deaths every year, particularly in tropical and subtropical regions. The World Health Organization has set a goal to halve the deaths an...
A clinical practical model for preoperative prediction of visual outcome for pituitary adenoma patients in a retrospective and prospective study.
Frontiers in endocrinology
Dec 13, 2024
OBJECTIVE: Preoperative prediction of visual recovery after pituitary adenoma resection surgery remains challenging. This study aimed to investigate the value of clinical and radiological features in preoperatively predicting visual outcomes after su...
IL-27 as a novel biomarker for pruritus in nodular prurigo and bullous pemphigoid.
Frontiers in immunology
Dec 13, 2024
INTRODUCTION: Bullous pemphigoid (BP) and prurigo nodularis (PN) are chronic pruritic skin diseases that severely impact patients' quality of life. Despite the widespread attention these two diseases have garnered within the dermatological field, the...
Development of a urine-based metabolomics approach for multi-cancer screening and tumor origin prediction.
Frontiers in immunology
Dec 13, 2024
BACKGROUND: Cancer remains a leading cause of mortality worldwide. A non-invasive screening solution was required for early diagnosis of cancer. Multi-cancer early detection (MCED) tests have been considered to address the challenge by simultaneously...
Predicting axillary lymph node metastasis in breast cancer using a multimodal radiomics and deep learning model.
Frontiers in immunology
Dec 13, 2024
OBJECTIVE: To explore the value of combined radiomics and deep learning models using different machine learning algorithms based on mammography (MG) and magnetic resonance imaging (MRI) for predicting axillary lymph node metastasis (ALNM) in breast c...
Machine learning-based radiomic features of perivascular adipose tissue in coronary computed tomography angiography predicting inflammation status around atherosclerotic plaque: a retrospective cohort study.
Annals of medicine
Dec 12, 2024
OBJECTIVES: This study expolored the relationship between perivascular adipose tissue (PVAT) radiomic features derived from coronary computed tomography angiography (CCTA) and the presence of coronary artery plaques. It aimed to determine whether PVA...
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