AIMC Topic: Radiation Injuries

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The application of artificial intelligence in the IMRT planning process for head and neck cancer.

Oral oncology Oct 31, 2018
Artificial intelligence (AI) is beginning to transform IMRT treatment planning for head and neck patients. However, the complexity and novelty of AI algorithms make them susceptible to misuse by researchers and clinicians. Understanding nuances of ne...
Head and Neck Neoplasms Radiotherapy Planning, Computer-Assisted Radiotherapy, Intensity-Modulated Radiation Injuries Radiation Oncologists Humans Machine Learning Clinical Decision-Making Clinical Competence
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Development of a Ready-to-Use Graphical Tool Based on Artificial Neural Network Classification: Application for the Prediction of Late Fecal Incontinence After Prostate Cancer Radiation Therapy.

International journal of radiation oncology, biology, physics Aug 6, 2018
PURPOSE: This study was designed to apply artificial neural network (ANN) classification methods for the prediction of late fecal incontinence (LFI) after high-dose prostate cancer radiation therapy and to develop a ready-to-use graphical tool.
Time Factors Prostatic Neoplasms Radiation Injuries Fecal Incontinence Humans Neural Networks, Computer Prognosis Male
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Distinguishing True Progression From Radionecrosis After Stereotactic Radiation Therapy for Brain Metastases With Machine Learning and Radiomics.

International journal of radiation oncology, biology, physics May 24, 2018
PURPOSE: Treatment effect or radiation necrosis after stereotactic radiosurgery (SRS) for brain metastases is a common phenomenon often indistinguishable from true progression. Radiomics is an emerging field that promises to improve on conventional i...
Aged, 80 and over Humans Diagnosis, Differential Adult Disease Progression Radiosurgery Brain Neoplasms Machine Learning Magnetic Resonance Imaging Radiation Injuries Aged Middle Aged
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A deep Boltzmann machine-driven level set method for heart motion tracking using cine MRI images.

Medical image analysis Apr 6, 2018
Heart motion tracking for radiation therapy treatment planning can result in effective motion management strategies to minimize radiation-induced cardiotoxicity. However, automatic heart motion tracking is challenging due to factors that include the ...
Neural Networks, Computer Algorithms Image Processing, Computer-Assisted Head and Neck Neoplasms Heart Humans Magnetic Resonance Imaging, Cine Motion Markov Chains Radiation Injuries Radiotherapy, Image-Guided
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Focal MRI-Guided Salvage High-Dose-Rate Brachytherapy in Patients With Radiorecurrent Prostate Cancer.

Technology in cancer research & treatment Dec 5, 2017
INTRODUCTION: Whole-gland salvage treatment of radiorecurrent prostate cancer has a high rate of severe toxicity. The standard of care in case of a biochemical recurrence is androgen deprivation treatment, which is associated with morbidity and negat...
Salvage Therapy Middle Aged Radiation Injuries Gallium Radioisotopes Humans Brachytherapy Glutamate Carboxypeptidase II Aged Prostatic Neoplasms Radiotherapy Dosage Aged, 80 and over Prostate Antigens, Surface Male Neoplasm Recurrence, Local
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Early prediction of radiotherapy-induced parotid shrinkage and toxicity based on CT radiomics and fuzzy classification.

Artificial intelligence in medicine Mar 18, 2017
MOTIVATION: Patients under radiotherapy for head-and-neck cancer often suffer of long-term xerostomia, and/or consistent shrinkage of parotid glands. In order to avoid these drawbacks, adaptive therapy can be planned for patients at risk, if the pred...
Parotid Gland Early Diagnosis Radiotherapy Dosage Radiation Injuries Fuzzy Logic Predictive Value of Tests Bayes Theorem Radiographic Image Interpretation, Computer-Assisted Radiation Exposure Cranial Irradiation Xerostomia Humans Risk Factors Time Factors Head and Neck Neoplasms Machine Learning Tomography, X-Ray Computed
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A Randomized Phase 2 Trial of Prophylactic Manuka Honey for the Reduction of Chemoradiation Therapy-Induced Esophagitis During the Treatment of Lung Cancer: Results of NRG Oncology RTOG 1012.

International journal of radiation oncology, biology, physics Nov 23, 2016
PURPOSE: Randomized trials have shown that honey is effective for the prevention of radiation-induced mucositis in head and neck cancer patients. Because there is no efficacious preventative for radiation esophagitis in lung cancer patients, this tri...
Treatment Outcome Humans Honey Female Chemoradiotherapy Radiation Injuries Diet Therapy Esophagitis Aged Leptospermum Male Middle Aged Lung Neoplasms
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Normal tissue complication probability (NTCP) modelling using spatial dose metrics and machine learning methods for severe acute oral mucositis resulting from head and neck radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology May 27, 2016
BACKGROUND AND PURPOSE: Severe acute mucositis commonly results from head and neck (chemo)radiotherapy. A predictive model of mucositis could guide clinical decision-making and inform treatment planning. We aimed to generate such a model using spatia...
Radiotherapy Dosage Radiation Injuries Stomatitis Models, Theoretical Head and Neck Neoplasms Acute Disease Probability Clinical Decision-Making Female Male Logistic Models Humans Machine Learning
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Accelerated partial breast irradiation using robotic radiotherapy: a dosimetric comparison with tomotherapy and three-dimensional conformal radiotherapy.

Radiation oncology (London, England) Feb 27, 2016
BACKGROUND: Accelerated partial breast irradiation (APBI) is a new breast treatment modality aiming to reduce treatment time using hypo fractionation. Compared to conventional whole breast irradiation that takes 5 to 6 weeks, APBI is reported to indu...
Humans Female Breast Neoplasms Radiosurgery Radiotherapy Imaging, Three-Dimensional Radiotherapy, Conformal Surgical Instruments Radiation Injuries Robotics Movement Respiration Phantoms, Imaging Breast Radiometry Radiotherapy Dosage Radiotherapy Planning, Computer-Assisted Radiotherapy, Intensity-Modulated
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Outcomes Associated With 3 Treatment Schedules of High-Dose-Rate Brachytherapy Monotherapy for Favorable-Risk Prostate Cancer.

International journal of radiation oncology, biology, physics Nov 10, 2015
PURPOSE: We report the outcomes associated with 3 high-dose-rate (HDR) brachytherapy regimens used as monotherapy for favorable-risk prostate cancer.
Brachytherapy Urination Disorders Risk Dose Fractionation, Radiation Radiation Injuries Urogenital System Prostatic Neoplasms Prostate-Specific Antigen Neoplasm Grading Aged Gastrointestinal Tract Time Factors Aged, 80 and over Humans Follow-Up Studies Adult Chronic Disease Male Acute Disease Middle Aged
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