AIMC Topic: Adiposity

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Using unsupervised machine learning methods to cluster cardio-metabolic profile of the middle-aged and elderly Chinese with general and central obesity.

BMC cardiovascular disorders
BACKGROUND: Obesity is a disease with high heterogeneity. Both overall obesity and central obesity are associated with increased risks of having cardio-metabolic co-morbidities. This study is aimed to examine the cardio-metabolic characteristics and ...

Markers of body fat, the mediating role of alanine aminotransferase, and their association with the risk of metabolic dysfunction-associated steatotic liver disease.

European journal of pediatrics
Metabolic dysfunction-associated steatotic liver disease (MASLD) in children with obesity correlates with metabolic dysfunction, yet interactions between anthropometrics, liver enzymes, and risk of MASLD remain unclear. This study included 219 childr...

AI-Driven segmentation and morphogeometric profiling of epicardial adipose tissue in type 2 diabetes.

Cardiovascular diabetology
BACKGROUND: Epicardial adipose tissue (EAT) is associated with cardiometabolic risk in type 2 diabetes (T2D), but its spatial distribution and structural alterations remain understudied. We aim to develop a shape-aware, AI-based method for automated ...

Deep learning and genome-wide association meta-analyses of bone marrow adiposity in the UK Biobank.

Nature communications
Bone marrow adipose tissue is a distinct adipose subtype comprising more than 10% of fat mass in healthy humans. However, the functions and pathophysiological correlates of this tissue are unclear, and its genetic determinants remain unknown. Here, w...

Accelerated chemical shift encoded cardiovascular magnetic resonance imaging with use of a resolution enhancement network.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
BACKGROUND: Cardiovascular magnetic resonance (CMR) chemical shift encoding (CSE) enables myocardial fat imaging. We sought to develop a deep learning network (fast chemical shift encoding [FastCSE]) to accelerate CSE.

Prediction of the 10-year incidence of type 2 diabetes mellitus based on advanced anthropometric indices using machine learning methods in the Iranian population.

Diabetes research and clinical practice
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a growing chronic disease that can lead to disability and early death. This study aimed to establish a predictive model for the 10-year incidence of T2DM based on novel anthropometric indices.

Gender-specific data-driven adiposity subtypes using deep-learning-based abdominal CT segmentation.

Obesity (Silver Spring, Md.)
OBJECTIVE: The aim of this study was to quantify abdominal adiposity and generate data-driven adiposity subtypes with different diabetes risks.

Fully automated CT-based adiposity assessment: comparison of the L1 and L3 vertebral levels for opportunistic prediction.

Abdominal radiology (New York)
PURPOSE: The purpose of this study is to compare fully automated CT-based measures of adipose tissue at the L1 level versus the standard L3 level for predicting mortality, which would allow for use at both chest (L1) and abdominal (L3) CT.