AIMC Topic: Aged

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Predictive modelling of knee osteoporosis.

BMC research notes
OBJECTIVE: The objective of this research was to develop a machine learning-based predictive model for osteoporosis screening using demographic and clinical data, including T-scores derived from calcaneus Quantitative Ultrasound (QUS). The study aime...

Freezing of gait detection: The effect of sensor type, position, activities, datasets, and machine learning model.

Journal of Parkinson's disease
BackgroundFreezing of gait (FoG) is a complex, frequent, and disabling motor symptom of Parkinson's disease (PD). Wearable technology has the potential to improve FoG assessment by providing objective, quantitative, and continuous monitoring.Objectiv...

Automated liver magnetic resonance elastography quality control and liver stiffness measurement using deep learning.

Abdominal radiology (New York)
PURPOSE: Magnetic resonance elastography (MRE) measures liver stiffness for fibrosis staging, but its utility can be hindered by quality control (QC) challenges and measurement variability. The objective of the study was to fully automate liver MRE Q...

Defining lipedema's molecular hallmarks by multi-omics approach for disease prediction in women.

Metabolism: clinical and experimental
Lipedema is a chronic disease in females characterized by pathologic subcutaneous adipose tissue expansion and hitherto remains without druggable targets. In this observational study, we investigated the molecular hallmarks of lipedema using an unbia...

Development of an artificial intelligence-generated, explainable treatment recommendation system for urothelial carcinoma and renal cell carcinoma to support multidisciplinary cancer conferences.

European journal of cancer (Oxford, England : 1990)
BACKGROUND: Decisions on the best available treatment in clinical oncology are based on expert opinions in multidisciplinary cancer conferences (MCC). Artificial intelligence (AI) could increase evidence-based treatment by generating additional treat...

AI Enhanced explainable early prediction of blood culture positivity in neutropenic patients using clinical and hematologic parameters.

Computers in biology and medicine
Leukemia patients who receive chemotherapy experience a decline in neutrophils and an increased risk of infections. Neutropenic sepsis is a life-threatening condition and a major cause of cancer-related mortality. Patients with neutropenic sepsis are...

Voxel-level radiomics and deep learning for predicting pathologic complete response in esophageal squamous cell carcinoma after neoadjuvant immunotherapy and chemotherapy.

Journal for immunotherapy of cancer
BACKGROUND: Accurate prediction of pathologic complete response (pCR) following neoadjuvant immunotherapy combined with chemotherapy (nICT) is crucial for tailoring patient care in esophageal squamous cell carcinoma (ESCC). This study aimed to develo...

Surrogate markers of insulin resistance and coronary artery disease in type 2 diabetes: U-shaped TyG association and insights from machine learning integration.

Lipids in health and disease
BACKGROUND: Surrogate insulin resistance (IR) indices are simpler and more practical alternatives to insulin-based IR indicators for clinical use. This study explored the association between surrogate IR indices, including triglyceride-glucose index ...

A MEMS seismometer respiratory monitor for work of breathing assessment and adventitious lung sounds detection via deep learning.

Scientific reports
Physicians evaluate a patient's respiratory health during a physical examination by visual assessment of the work of breathing (WoB) to determine respiratory stability, and by detecting abnormal lung sounds via lung auscultation using a stethoscope t...