Treatment selection is becoming increasingly more important in acute ischemic stroke patient care. Clinical variables and radiological image biomarkers (old age, pre-stroke mRS, NIHSS, occlusion location, ASPECTS, among others) have an important role...
Background Fixed airflow limitation and ventilation heterogeneity are common in chronic obstructive pulmonary disease (COPD). Conventional noncontrast CT provides airway and parenchymal measurements but cannot be used to directly determine lung funct...
BackgroundThe performance of a deep learning (DL) algorithm should be validated in actual clinical situations, before its clinical implementation.PurposeTo evaluate the performance of a DL algorithm for identifying chest radiographs with clinically r...
INTRODUCTION: The cardiac radiation dose is an important predictor of cardiac toxicity and overall survival (OS) for patients with locally advanced non-small-cell lung cancer (NSCLC). However, radiation-induced cardiac toxicity among patients with ea...
Clinical cancer research : an official journal of the American Association for Cancer Research
Oct 21, 2019
PURPOSE: Biomarkers for disease-specific survival (DSS) in early-stage melanoma are needed to select patients for adjuvant immunotherapy and accelerate clinical trial design. We present a pathology-based computational method using a deep neural netwo...
Neuroanatomical segmentation in magnetic resonance imaging (MRI) of the brain is a prerequisite for quantitative volume, thickness, and shape measurements, as well as an important intermediate step in many preprocessing pipelines. This work introduce...
BACKGROUND: Cardiovascular outcomes for people with familial hypercholesterolaemia can be improved with diagnosis and medical management. However, 90% of individuals with familial hypercholesterolaemia remain undiagnosed in the USA. We aimed to accel...
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Oct 21, 2019
The identification of high-grade glioma (HGG) progression may pose a diagnostic dilemma due to similar appearances of treatment-related changes (TRC) (e.g. pseudoprogression or radionecrosis). Deep learning (DL) may be able to assist with this task. ...
Machine learning has the potential to identify novel biological factors underlying successful antibody responses to influenza vaccines. The first attempts have revealed a high level of complexity in establishing influenza immunity, and many different...
Computational and mathematical methods in medicine
Oct 20, 2019
Motion artifacts and myoelectrical noise are common issues complicating the collection and processing of dynamic electrocardiogram (ECG) signals. Recent signal quality studies have utilized a binary classification metric in which ECG samples are dete...
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