AIMC Topic: Alanine Transaminase

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Utilization of Deep Learning for Subphenotype Identification in Sepsis-Associated Acute Kidney Injury.

Clinical journal of the American Society of Nephrology : CJASN Oct 8, 2020
BACKGROUND AND OBJECTIVES: Sepsis-associated AKI is a heterogeneous clinical entity. We aimed to agnostically identify sepsis-associated AKI subphenotypes using deep learning on routinely collected data in electronic health records.
Aged Male Middle Aged Comorbidity Phenotype Humans Deep Learning Databases, Factual Sepsis Lactic Acid Renal Dialysis Prognosis United States Acute Kidney Injury Liver Diseases Creatinine Electronic Health Records Blood Urea Nitrogen L-Lactate Dehydrogenase Female Leukocyte Count Alanine Transaminase Simplified Acute Physiology Score Bilirubin Glutamyl Aminopeptidase
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Predictive Estimates of Risks Associated with Type 2 Diabetes Mellitus on the Basis of Biochemical Biomarkers and Derived Time-Dependent Parameters.

Journal of computational biology : a journal of computational molecular cell biology Apr 17, 2019
Prognosis Humans Female Blood Glucose Machine Learning Risk Factors Diabetes Mellitus, Type 2 Biomarkers Male Cholesterol Risk Assessment Alanine Transaminase Big Data Aspartate Aminotransferases
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Machine Learning-based Development and Validation of a Scoring System for Screening High-Risk Esophageal Varices.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Jan 29, 2019
BACKGROUND & AIMS: Many patients with cirrhosis who undergo esophagogastroduodenoscopy (EGD) screening for esophageal varices (EVs) are found to have no or only small EVs. Endoscopic screening for EVs is therefore a potentially deferrable procedure t...
Female Aged Male Middle Aged Risk Assessment Severity of Illness Index Humans Machine Learning Prospective Studies Non-alcoholic Fatty Liver Disease Hemoglobins Sodium Platelet Count Hepatitis C, Chronic Alanine Transaminase Liver Cirrhosis Mass Screening International Normalized Ratio Esophageal and Gastric Varices Ascites Creatinine Blood Urea Nitrogen Aspartate Aminotransferases Endoscopy, Digestive System Bilirubin Thrombocytopenia Liver Cirrhosis, Alcoholic Gastrointestinal Hemorrhage Hepatic Encephalopathy Serum Albumin
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Application of Machine Learning Methods to Predict Non-Alcoholic Steatohepatitis (NASH) in Non-Alcoholic Fatty Liver (NAFL) Patients.

AMIA ... Annual Symposium proceedings. AMIA Symposium Dec 5, 2018
Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease worldwide. NAFLD patients have excessive liver fat (steatosis), without other liver diseases and without excessive alcohol consumption. NAFLD consists of a spectr...
Diabetes Mellitus, Type 2 Supervised Machine Learning Fatty Liver Aged Humans Non-alcoholic Fatty Liver Disease Logistic Models Male Biomarkers Hepatitis Liver Cirrhosis Middle Aged Electronic Health Records Alanine Transaminase Health Status Disease Progression Female Aspartate Aminotransferases Decision Trees Case-Control Studies Risk Factors Liver Function Tests Cohort Studies
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Application of Machine Learning Techniques for Clinical Predictive Modeling: A Cross-Sectional Study on Nonalcoholic Fatty Liver Disease in China.

BioMed research international Oct 3, 2018
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases. Machine learning techniques were introduced to evaluate the optimal predictive clinical model of NAFLD.
gamma-Glutamyltransferase Alanine Transaminase Triglycerides Humans Machine Learning Female Adult Cross-Sectional Studies Male Middle Aged China Body Mass Index Models, Biological Non-alcoholic Fatty Liver Disease
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Plasminogen activator inhibitor-1 is associated with the metabolism and development of advanced colonic polyps.

Translational research : the journal of laboratory and clinical medicine Jun 6, 2018
Implications of plasminogen activator inhibitor-1 (PAI-1) in colonic polyps remain elusive. A prospective study was conducted with 188 consecutive subjects who underwent colonoscopy at a tertiary referral center. Biochemical parameters, serum PAI-1 l...
Colonoscopy Homeostasis ROC Curve Plasminogen Activator Inhibitor 1 Polymorphism, Single Nucleotide Cholesterol, HDL Genotype Insulin Resistance Humans Colonic Polyps Adenoma Prospective Studies Platelet Count Female Alanine Transaminase Aged Triglycerides Male Middle Aged
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Correlations of Complete Blood Count with Alanine and Aspartate Transaminase in Chinese Subjects and Prediction Based on Back-Propagation Artificial Neural Network (BP-ANN).

Medical science monitor : international medical journal of experimental and clinical research Jun 19, 2017
BACKGROUND The complete blood count (CBC) is the most common examination used to monitor overall health in clinical practice. Whether there is a relationship between CBC indexes and alanine transaminase (ALT) and aspartate aminotransferase (AST) has ...
Female Adult Male Overweight Regression Analysis Asian People Alanine Transaminase Aspartate Aminotransferases Humans Blood Cell Count Neural Networks, Computer
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Laboratory parameter-based machine learning model for excluding non-alcoholic fatty liver disease (NAFLD) in the general population.

Alimentary pharmacology & therapeutics Jun 6, 2017
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) affects 20%-40% of the general population in developed countries and is an increasingly important cause of hepatocellular carcinoma. Electronic medical records facilitate large-scale epidemiologic...
Triglycerides ROC Curve Logistic Models Non-alcoholic Fatty Liver Disease Anthropometry Alanine Transaminase Lipoproteins, HDL Adult Sensitivity and Specificity Humans Cross-Sectional Studies Male Machine Learning Middle Aged Female
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ANTIOXIDANT ACTIVITY AND HEPATOPROTECTIVE EFFECTS OF COMPOUND .

African journal of traditional, complementary, and alternative medicines : AJTCAM Aug 12, 2016
BACKGROUND: Chinese medicine has its own uniqueness, advantageous in the treatment of hepatic diseases, and they were widely used in the oxidation. At the same time, oxidation is one of the mechanism of protect liver.
Lobelia Animals Aspartate Aminotransferases Male Benzothiazoles Mice Sulfonic Acids Antioxidants Phytotherapy Malondialdehyde Carbon Tetrachloride Chemical and Drug Induced Liver Injury Superoxide Dismutase Liver Protective Agents Oxidation-Reduction Drugs, Chinese Herbal Alanine Transaminase
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Development and Validation of an Algorithm to Identify Nonalcoholic Fatty Liver Disease in the Electronic Medical Record.

Digestive diseases and sciences Nov 4, 2015
BACKGROUND AND AIMS: Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. Risk factors for NAFLD disease progression and liver-related outcomes remain incompletely understood due to the lack of computa...
Humans Algorithms Electronic Health Records Female Aged Adult Male Middle Aged Alanine Transaminase Prevalence United States Aspartate Aminotransferases Cohort Studies Diabetes Mellitus Logistic Models Natural Language Processing International Classification of Diseases Biopsy Triglycerides Non-alcoholic Fatty Liver Disease Data Collection
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