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Alanine Transaminase

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Application of Machine Learning Methods to Predict Non-Alcoholic Steatohepatitis (NASH) in Non-Alcoholic Fatty Liver (NAFL) Patients.

AMIA ... Annual Symposium proceedings. AMIA Symposium 30815083
Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease worldwide. NAFLD patients have excessive liver fat (steatosis), without other liver diseases and without excessive alcohol consumption. NAFLD consists of a spectr...
Aged Alanine Transaminase Aspartate Aminotransferases Biomarkers Case-Control Studies Cohort Studies Decision Trees Diabetes Mellitus, Type 2 Disease Progression Electronic Health Records Fatty Liver Female Health Status Hepatitis Humans Liver Cirrhosis Liver Function Tests Logistic Models Male Middle Aged Non-alcoholic Fatty Liver Disease Risk Factors Supervised Machine Learning
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Plasminogen activator inhibitor-1 is associated with the metabolism and development of advanced colonic polyps.

Translational research : the journal of laboratory and clinical medicine 30670154
Implications of plasminogen activator inhibitor-1 (PAI-1) in colonic polyps remain elusive. A prospective study was conducted with 188 consecutive subjects who underwent colonoscopy at a tertiary referral center. Biochemical parameters, serum PAI-1 l...
Adenoma Aged Alanine Transaminase Cholesterol, HDL Colonic Polyps Colonoscopy Female Genotype Homeostasis Humans Insulin Resistance Male Middle Aged Plasminogen Activator Inhibitor 1 Platelet Count Polymorphism, Single Nucleotide Prospective Studies ROC Curve Triglycerides
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The Hepatoprotective Effect of Clidemia hirta against Carbon Tetrachloride (CCl4)-Induced Oxidative Stress and Hepatic Damage in Mice.

Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 29431062
Liver diseases still represents a major health burden worldwide. Moreover, medicinal plants have gained popularity in the treatment of several diseases, including liver disease. Clidemia hirta possesses many medicinal properties for healing several d...
Alanine Transaminase Animals Aspartate Aminotransferases Carbon Tetrachloride Lipid Peroxidation Liver Male Melastomataceae Mice Mice, Inbred BALB C Oxidative Stress Plant Extracts
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ANTIOXIDANT ACTIVITY AND HEPATOPROTECTIVE EFFECTS OF COMPOUND .

African journal of traditional, complementary, and alternative medicines : AJTCAM 28487901
BACKGROUND: Chinese medicine has its own uniqueness, advantageous in the treatment of hepatic diseases, and they were widely used in the oxidation. At the same time, oxidation is one of the mechanism of protect liver.
Alanine Transaminase Animals Antioxidants Aspartate Aminotransferases Benzothiazoles Carbon Tetrachloride Chemical and Drug Induced Liver Injury Drugs, Chinese Herbal Liver Lobelia Male Malondialdehyde Mice Oxidation-Reduction Phytotherapy Protective Agents Sulfonic Acids Superoxide Dismutase
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Antioxidant and hepatoprotective activities of Dicoma anomala Sond. aqueous root extract against carbon tetrachloride-induced liver damage in Wistar rats.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 28459518
OBJECTIVE: To evaluates the antioxidant and hepatoprotective potentials of Dicoma anomala Sond. (Asteraceae) on body weight, feed and water intake, biochemical parameters and organ histology.
Alanine Transaminase Animals Antioxidants Aspartate Aminotransferases Asteraceae Carbon Tetrachloride Chemical and Drug Induced Liver Injury Drugs, Chinese Herbal Female Humans Liver Male Plant Roots Protective Agents Rats Rats, Wistar Superoxide Dismutase
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Protective effect of Yiguanjian decoction against DNA damage on concanavalin A-induced liver injury mice model.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 28459511
OBJECTIVE: To investigate the inhibitory effect of Yiguanjian decoction (YD) on DNA damage in Concanavalin A (Con A)-induced liver injury mice model and to explain the possible mechanism.
Alanine Transaminase Animals Aspartate Aminotransferases Chemical and Drug Induced Liver Injury Concanavalin A Disease Models, Animal DNA Damage Drugs, Chinese Herbal Humans Liver Male Mice Mice, Inbred BALB C Protective Agents
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Correlations of Complete Blood Count with Alanine and Aspartate Transaminase in Chinese Subjects and Prediction Based on Back-Propagation Artificial Neural Network (BP-ANN).

Medical science monitor : international medical journal of experimental and clinical research 28628604
BACKGROUND The complete blood count (CBC) is the most common examination used to monitor overall health in clinical practice. Whether there is a relationship between CBC indexes and alanine transaminase (ALT) and aspartate aminotransferase (AST) has ...
Adult Alanine Transaminase Asian People Aspartate Aminotransferases Blood Cell Count Female Humans Male Neural Networks, Computer Overweight Regression Analysis
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Laboratory parameter-based machine learning model for excluding non-alcoholic fatty liver disease (NAFLD) in the general population.

Alimentary pharmacology & therapeutics 28585725
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) affects 20%-40% of the general population in developed countries and is an increasingly important cause of hepatocellular carcinoma. Electronic medical records facilitate large-scale epidemiologic...
Adult Alanine Transaminase Anthropometry Cross-Sectional Studies Female Humans Lipoproteins, HDL Logistic Models Machine Learning Male Middle Aged Non-alcoholic Fatty Liver Disease ROC Curve Sensitivity and Specificity Triglycerides
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Application of Machine Learning Techniques for Clinical Predictive Modeling: A Cross-Sectional Study on Nonalcoholic Fatty Liver Disease in China.

BioMed research international 30402478
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases. Machine learning techniques were introduced to evaluate the optimal predictive clinical model of NAFLD.
Adult Alanine Transaminase Body Mass Index China Cross-Sectional Studies Female gamma-Glutamyltransferase Humans Machine Learning Male Middle Aged Models, Biological Non-alcoholic Fatty Liver Disease Triglycerides
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Machine Learning-based Development and Validation of a Scoring System for Screening High-Risk Esophageal Varices.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 30708109
BACKGROUND & AIMS: Many patients with cirrhosis who undergo esophagogastroduodenoscopy (EGD) screening for esophageal varices (EVs) are found to have no or only small EVs. Endoscopic screening for EVs is therefore a potentially deferrable procedure t...
Aged Alanine Transaminase Ascites Aspartate Aminotransferases Bilirubin Blood Urea Nitrogen Creatinine Endoscopy, Digestive System Esophageal and Gastric Varices Female Gastrointestinal Hemorrhage Hemoglobins Hepatic Encephalopathy Hepatitis C, Chronic Humans International Normalized Ratio Liver Cirrhosis Liver Cirrhosis, Alcoholic Machine Learning Male Mass Screening Middle Aged Non-alcoholic Fatty Liver Disease Platelet Count Prospective Studies Risk Assessment Serum Albumin Severity of Illness Index Sodium Thrombocytopenia
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