AIMC Topic: Alkaline Phosphatase
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An Individualized Prediction Model for Long-term Lung Function Trajectory and Risk of COPD in the General Population.
Chest
Sep 19, 2019
BACKGROUND: Prediction of future lung function will enable the identification of individuals at high risk of developing COPD, but the trajectory of lung function decline varies greatly among individuals. This study involved the development and valida...
Cigarette Smoking
Alkaline Phosphatase
Hematocrit
Adult
Pulmonary Disease, Chronic Obstructive
Dyspnea
Sex Factors
Male
Aging
Middle Aged
Risk Assessment
Lung
Cohort Studies
Longitudinal Studies
Serum Albumin
Electrocardiography
Age Factors
Leukocyte Count
Cough
Humans
Vital Capacity
Forced Expiratory Volume
Machine Learning
Bronchodilator Agents
Algorithms
Serum Globulins
Body Height
Female
Alcohol Drinking
Spirometry
Triglycerides
Exploration of the nanomedicine-design space with high-throughput screening and machine learning.
Nature biomedical engineering
Feb 18, 2019
Only a tiny fraction of the nanomedicine-design space has been explored, owing to the structural complexity of nanomedicines and the lack of relevant high-throughput synthesis and analysis methods. Here, we report a methodology for determining struct...
Unlocking the hidden talent of DNA: Unexpected catalytic activity for colorimetric assay of alkaline phosphatase.
Analytica chimica acta
Dec 21, 2018
Carboxylic acids have been efficiently used to activate HO to form even more potent oxidant-peroxy acids through enzyme-catalyzed processes. By employing acetic acid as the activator, herein we report for the first time that cofactor-free DNA display...
Near-infrared mito-specific fluorescent probe for ratiometric detection and imaging of alkaline phosphatase activity with high sensitivity.
Journal of materials chemistry. B
Dec 19, 2018
Fluorescent probe-based analytical methods for biological species have gained increasing attention for their powerful detection and imaging capabilities. However, it is still occasionally problematic for accurate analyses due to the influence of the ...
Molecular structure regulation and enzyme cascade signal amplification strategy for upconversion ratiometric luminescent and colorimetric alkaline phosphatase detection.
Analytica chimica acta
Nov 15, 2018
Herein, molecular structure regulation and enzyme cascade signals amplification (MRECAmp) strategy was proposed to construct a novel upconversion ratiometric fluorescence and colorimetric dual-readout assay platform for highly sensitive and selective...
Prognostic models in primary biliary cholangitis.
Journal of autoimmunity
Nov 9, 2018
Risk prediction modelling is important to better understand the determinants of the course and outcome of PBC and to inform the risk across the disease continuum in PBC enabling risk-stratified follow-up care and personalised therapy. Current prognos...
Simvastatin and nanofibrous poly(l-lactic acid) scaffolds to promote the odontogenic potential of dental pulp cells in an inflammatory environment.
Acta biomaterialia
Dec 30, 2017
UNLABELLED: In this study, we investigated the anti-inflammatory, odontogenic and pro-angiogenic effects of integrating simvastatin and nanofibrous poly(l-lactic acid) (NF-PLLA) scaffolds on dental pulp cells (DPCs). Highly porous NF-PLLA scaffolds t...
Humans
Biomarkers
Young Adult
Gene Expression Regulation
RNA, Messenger
Tissue Scaffolds
Inflammation
Simvastatin
Human Umbilical Vein Endothelial Cells
Nanofibers
Signal Transduction
Cytoprotection
Odontogenesis
Alkaline Phosphatase
Lipopolysaccharides
Mesenchymal Stem Cells
Dental Pulp
Neovascularization, Physiologic
Cell Differentiation
Polyesters
Baicalin inhibits Escherichia coli isolates in bovine mastitic milk and reduces antimicrobial resistance.
Journal of dairy science
Dec 28, 2017
In this study, we aimed to evaluate the inhibitory effect of baicalin on Escherichia coli in vitro and the effects of baicalin treatment on antimicrobial resistance of the E. coli isolates. Through isolation, purification, and identification, a total...
Enhancement of lateral flow immunoassay by alkaline phosphatase: a simple and highly sensitive test for potato virus X.
Mikrochimica acta
Dec 6, 2017
Alkaline phosphatase (ALP) was used as an amplification tool in lateral flow immunoassay (LFIA). Potato virus Х (PVX) was selected as a target analyte because of its high economic importance. Two conjugates of gold nanoparticles were applied, one wit...
Vitamin D status in children with headache: A case-control study.
Clinical nutrition ESPEN
Oct 13, 2017
BACKGROUND: Vitamin D is a fat soluble vitamin with hormonal properties, plays crucial functions in bone and mineral metabolism and has important regulatory functions in brain development, cell differentiation and apoptosis. Some studies have shown a...
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