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Calcium

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Predicting Renal Failure Progression in Chronic Kidney Disease Using Integrated Intelligent Fuzzy Expert System.

Computational and mathematical methods in medicine
BACKGROUND: Chronic kidney disease (CKD) is a covert disease. Accurate prediction of CKD progression over time is necessary for reducing its costs and mortality rates. The present study proposes an adaptive neurofuzzy inference system (ANFIS) for pre...

Abnormal calcium, 25(OH)vitamin D, and parathyroid hormone after biliopancreatic diversion; correction through elongation of the common tract and reduction of the gastric pouch.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
BACKGROUND: Biliopancreatic diversion (BPD) is a surgical technique burdened, in some instances, by clinical evidence of malabsorption and intractable diarrhoea.

Using support vector machines to improve elemental ion identification in macromolecular crystal structures.

Acta crystallographica. Section D, Biological crystallography
In the process of macromolecular model building, crystallographers must examine electron density for isolated atoms and differentiate sites containing structured solvent molecules from those containing elemental ions. This task requires specific know...

GTM-Based QSAR Models and Their Applicability Domains.

Molecular informatics
In this paper we demonstrate that Generative Topographic Mapping (GTM), a machine learning method traditionally used for data visualisation, can be efficiently applied to QSAR modelling using probability distribution functions (PDF) computed in the l...

CaML: Chemistry-informed machine learning explains mutual changes between protein conformations and calcium ions in calcium-binding proteins using structural and topological features.

Protein science : a publication of the Protein Society
Proteins' flexibility is a feature in communicating changes in cell signaling instigated by binding with secondary messengers, such as calcium ions, associated with the coordination of muscle contraction, neurotransmitter release, and gene expression...

Influence of vitamin D and calcium-sensing receptor gene variants on calcium metabolism in end-stage renal disease: insights from machine learning analysis.

European review for medical and pharmacological sciences
OBJECTIVE: End-stage renal disease (ESRD) commonly manifests with disrupted calcium balance, leading to renal osteodystrophy. We posited that variations in the genetic makeup of vitamin D and calcium-sensing receptors, specifically single nucleotide ...

Improved Segmentation of Confocal Calcium Videos of Hela Cells Using Deep-Learning-Assisted Watershed Algorithm.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
The potential of calcium imaging in high-throughput drug screening experiments remains underutilized, primarily because of time-intensive manual identification of cells.To overcome these challenges, we propose to use deep learning enhanced watershed ...