AIMC Topic: Case-Control Studies

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A comparison of machine learning techniques for classification of HIV patients with antiretroviral therapy-induced mitochondrial toxicity from those without mitochondrial toxicity.

BMC medical research methodology
BACKGROUND: Antiretroviral therapy (ART) has significantly reduced HIV-related morbidity and mortality. However, therapeutic benefit of ART is often limited by delayed drug-associated toxicity. Nucleoside reverse transcriptase inhibitors (NRTIs) are ...

Different spexin level in obese vs normal weight children and its relationship with obesity related risk factors.

Nutrition, metabolism, and cardiovascular diseases : NMCD
BACKGROUND AND AIMS: Spexin (SPX) is a novel peptide recently discovered as an important regulatory adipokine in obesity and related metabolic diseases. The aim of the current study was to determine the potential role of Circulating levels of SPX in ...

[Expression of plasma microRNA in patients with acromegaly].

Problemy endokrinologii
BACKGROUND: microRNA is a class of small non-coding RNA molecules involved in posttranscriptional regulation of gene expression. MicroRNAs are detectable in blood in stable concentrations, which makes them promising biomarkers for various diseases.

An improved fuzzy set-based multifactor dimensionality reduction for detecting epistasis.

Artificial intelligence in medicine
OBJECTIVE: Epistasis identification is critical for determining susceptibility to human genetic diseases. The rapid development of technology has enabled scalability to make multifactor dimensionality reduction (MDR) measurements an effective calcula...

The diagnostic and prognostic roles of serum irisin in bladder cancer.

Current problems in cancer
BACKGROUND: Egypt is among the countries with the highest incidence of bladder cancer (BC). Adipokines involved in BC development. This study aimed to examine the diagnostic and prognostic roles of irisin in BC through its function as an adipokine.

Deep learning modeling using normal mammograms for predicting breast cancer risk.

Medical physics
PURPOSE: To investigate two deep learning-based modeling schemes for predicting short-term risk of developing breast cancer using prior normal screening digital mammograms in a case-control setting.

Genetic Variation in Cytochrome P450 2R1 and Vitamin D Binding Protein Genes are associated with Vitamin D Deficiency in Adolescents.

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition
Genome Wide Association Studies (GWAS) have evaluated several genes related to vitamin D synthesis, metabolism and transport. They have proposed a genetic basis for low levels of vitamin D in the blood. The current study aims to investigate the rela...

Automated detection of focal cortical dysplasia using a deep convolutional neural network.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Focal cortical dysplasia (FCD) is one of the commonest epileptogenic lesions, and is related to malformations of the cortical development. The findings on magnetic resonance (MR) images are important for the diagnosis and surgical planning of FCD. In...

Non-invasive diagnosis of non-alcoholic steatohepatitis and fibrosis with the use of omics and supervised learning: A proof of concept study.

Metabolism: clinical and experimental
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) affects 25-30% of the general population and is characterized by the presence of non-alcoholic fatty liver (NAFL) that can progress to non-alcoholic steatohepatitis (NASH), liver fibrosis and cirr...

Analysis of nonstandardized stress echocardiography sequences using multiview dimensionality reduction.

Medical image analysis
Alternative stress echocardiography protocols such as handgrip exercise are potentially more favorable towards large-scale screening scenarios than those currently adopted in clinical practice. However, these are still underexplored because the maxim...