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Knowledge-Based Planning for Identifying High-Risk Stereotactic Ablative Radiation Therapy Treatment Plans for Lung Tumors Larger Than 5 cm.

International journal of radiation oncology, biology, physics Aug 14, 2018
PURPOSE: Stereotactic ablative body radiation therapy (SABR) for lung tumors ≥5 cm can be associated with more toxicity than that for smaller tumors. We investigated the relationship between dosimetry and toxicity and used a knowledge-based planning ...
Organs at Risk Radiotherapy Planning, Computer-Assisted Radiotherapy Dosage Radiosurgery Humans Lung Neoplasms Knowledge Bases
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Applications of machine learning algorithms to predict therapeutic outcomes in depression: A meta-analysis and systematic review.

Journal of affective disorders Aug 14, 2018
BACKGROUND: No previous study has comprehensively reviewed the application of machine learning algorithms in mood disorders populations. Herein, we qualitatively and quantitatively evaluate previous studies of machine learning-devised models that pre...
Adult Male Diagnosis, Computer-Assisted Treatment Outcome Neuroimaging Antidepressive Agents Depressive Disorder Machine Learning Algorithms Retrospective Studies Humans Female
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Live remote digital microscopy in peripheral blood smear evaluation: Intraobserver concordance and experience.

International journal of laboratory hematology Aug 14, 2018
INTRODUCTION: Peripheral blood smear (PBS) review is a routine laboratory test which requires pathologist's interpretation when abnormal indices, atypical cells, or critical findings are identified. Real-time remote digital microscopy (DM) can potent...
Female Male Image Processing, Computer-Assisted Robotics Humans Microscopy Observer Variation Blood Cells
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Identification of novel immune-relevant drug target genes for Alzheimer's Disease by combining ontology inference with network analysis.

CNS neuroscience & therapeutics Aug 14, 2018
AIMS: Alzheimer's disease (AD) is one of the leading causes of death in elderly people. Its pathogenesis is greatly associated with the abnormality of immune system. However, only a few immune-relevant AD drug target genes have been discovered up to ...
Gene Expression Profiling Alzheimer Disease Gene Regulatory Networks Antipsychotic Agents Humans Genetic Predisposition to Disease Gene Ontology Databases, Factual Signal Transduction Drug Delivery Systems Animals
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Risk prediction using natural language processing of electronic mental health records in an inpatient forensic psychiatry setting.

Journal of biomedical informatics Aug 14, 2018
OBJECTIVE: Instruments rating risk of harm to self and others are widely used in inpatient forensic psychiatry settings. A potential alternate or supplementary means of risk prediction is from the automated analysis of case notes in Electronic Health...
Humans Mental Health Services Ethics, Medical Regression Analysis Sensitivity and Specificity Unified Medical Language System Algorithms Inpatients Mental Health Forensic Psychiatry Electronic Health Records Natural Language Processing Tasmania Reproducibility of Results Risk Assessment Support Vector Machine
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Real-Time Use of Artificial Intelligence in Identification of Diminutive Polyps During Colonoscopy: A Prospective Study.

Annals of internal medicine Aug 14, 2018
BACKGROUND: Computer-aided diagnosis (CAD) for colonoscopy may help endoscopists distinguish neoplastic polyps (adenomas) requiring resection from nonneoplastic polyps not requiring resection, potentially reducing cost.
Aged Sensitivity and Specificity Male Middle Aged Artificial Intelligence Prospective Studies Female Coloring Agents Colonic Polyps Methylene Blue Narrow Band Imaging Humans Colonoscopy Diagnosis, Computer-Assisted Adenoma Feasibility Studies
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Automated prediction of dosimetric eligibility of patients with prostate cancer undergoing intensity-modulated radiation therapy using a convolutional neural network.

Radiological physics and technology Aug 14, 2018
The quality of radiotherapy has greatly improved due to the high precision achieved by intensity-modulated radiation therapy (IMRT). Studies have been conducted to increase the quality of planning and reduce the costs associated with planning through...
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Radiotherapy Dosage Radiotherapy, Intensity-Modulated Radiometry Humans Neural Networks, Computer Tomography, X-Ray Computed Male Prostatic Neoplasms Radiotherapy Planning, Computer-Assisted Automation
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Designing robot-assisted neurorehabilitation strategies for people with both HIV and stroke.

Journal of neuroengineering and rehabilitation Aug 14, 2018
There is increasing evidence that HIV is an independent risk factor for stroke, resulting in an emerging population of people living with both HIV and stroke all over the world. However, neurorehabilitation strategies for the HIV-stroke population ar...
Humans Comorbidity HIV Infections Robotics Stroke Exercise Therapy Stroke Rehabilitation
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Integration of Gene Expression Profile Data to Screen and Verify Hub Genes Involved in Osteoarthritis.

BioMed research international Aug 14, 2018
Osteoarthritis (OA) is one of the most common diseases worldwide, but the pathogenic genes and pathways are largely unclear. The aim of this study was to screen and verify hub genes involved in OA and explore potential molecular mechanisms. The expre...
Gene Ontology China Gene Regulatory Networks Computational Biology Osteoarthritis Humans Gene Expression Profiling Transcriptome
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Artificial neural networks help to identify disease subsets and to predict lymphoma in primary Sjögren's syndrome.

Clinical and experimental rheumatology Aug 14, 2018
OBJECTIVES: Primary Sjögren's syndrome (pSS) is a complex chronic systemic disorder, for which specific and effective therapeutic interventions are still lacking. In this era of precision medicine, there is a clear need for a better definition of dis...
Aged Male Middle Aged Disease Progression Serologic Tests Predictive Value of Tests Humans Female Sjogren's Syndrome Principal Component Analysis Neural Networks, Computer Decision Support Techniques Reproducibility of Results Severity of Illness Index Autoantibodies Risk Factors Data Mining Diagnosis, Computer-Assisted Phenotype Lymphoma Biomarkers Diagnosis, Differential Prognosis
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