Clinical chemistry and laboratory medicine
Sep 25, 2025
OBJECTIVES: Machine learning (ML) models, using laboratory data, support early sepsis prediction. However, analytical bias in laboratory measurements can compromise their performance and validity in real-world settings. We aimed to evaluate how analy...
BACKGROUND: Relapse and drug resistance are major contributor to chemotherapy failure in diffuse large B-cell lymphoma (DLBCL). Programmed cell death (PCD), a key mechanism in tumor progression and resistance, has emerged as a promising biomarker for...
Vascular dementia (VaD), the second most common form of dementia, lacks reliable biomarkers for early diagnosis. Here, we integrated weighted gene co-expression network analysis (WGCNA) with machine learning to identify novel biomarkers and immune-me...
The prediction and management of sudden cardiac death risk continue to pose significant challenges in cardiovascular care despite advances in therapies over the last two decades. Late gadolinium enhancement (LGE) on cardiac magnetic resonance-a marke...
Molecular dynamics (MD) simulations are fundamental for probing the structural dynamics of biomolecules, yet their efficiency is limited by the high computational cost of exploring long-timescale events. Generative machine learning (ML) models, parti...
AIMS: The aim of this research is to diagnose polycythaemia vera (PV) disease using different machine learning (ML) algorithms with complete blood count (CBC) parameters before further investigations such as Janus kinase 2 (), erythropoietin (EPO) an...
Cancer remains a major threat to human health, with the incidence of hepatobiliary tumors consistently high. Treatment methods for hepatobiliary tumors include surgical intervention, ablation, embolization, and pharmacological treatments, with surger...
Arsenic (As) exposure to rice threatens food safety while transferring As to rice from paddy soils significantly impacts increasing As levels in rice. This study explores establishing an efficient model for predicting As accumulation in rice grain us...
Differentiating the composition of Dissolved Organic Matter (DOM) in estuaries is a major environmental concern, as the DOM characteristics are closely linked to biogeochemical and ecological considerations (e.g. water properties and trophic cycling)...
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