AIMC Topic: Middle Aged

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Prediction of 7-year's conversion from subjective cognitive decline to mild cognitive impairment.

Human brain mapping
Subjective cognitive decline (SCD) is a high-risk yet less understood status before developing Alzheimer's disease (AD). This work included 76 SCD individuals with two (baseline and 7 years later) neuropsychological evaluations and a baseline T1-weig...

Utilization of Deep Learning for Subphenotype Identification in Sepsis-Associated Acute Kidney Injury.

Clinical journal of the American Society of Nephrology : CJASN
BACKGROUND AND OBJECTIVES: Sepsis-associated AKI is a heterogeneous clinical entity. We aimed to agnostically identify sepsis-associated AKI subphenotypes using deep learning on routinely collected data in electronic health records.

MRI-based machine learning radiomics can predict HER2 expression level and pathologic response after neoadjuvant therapy in HER2 overexpressing breast cancer.

EBioMedicine
BACKGROUND: To use clinical and MRI radiomic features coupled with machine learning to assess HER2 expression level and predict pathologic response (pCR) in HER2 overexpressing breast cancer patients receiving neoadjuvant chemotherapy (NAC).

Artificial intelligence quantified tumour-stroma ratio is an independent predictor for overall survival in resectable colorectal cancer.

EBioMedicine
BACKGROUND: An artificial intelligence method could accelerate the clinical implementation of tumour-stroma ratio (TSR), which has prognostic relevance in colorectal cancer (CRC). We, therefore, developed a deep learning model for the fully automated...

Data mining of human plasma proteins generates a multitude of highly predictive aging clocks that reflect different aspects of aging.

Aging cell
We previously identified 529 proteins that had been reported by multiple different studies to change their expression level with age in human plasma. In the present study, we measured the q-value and age coefficient of these proteins in a plasma prot...

Facial erythema detects diabetic neuropathy using the fusion of machine learning, random matrix theory and self organized criticality.

Scientific reports
Rubeosis faciei diabeticorum, caused by microangiopathy and characterized by a chronic facial erythema, is associated with diabetic neuropathy. In clinical practice, facial erythema of patients with diabetes is evaluated based on subjective observati...

Clinical predictive modelling of post-surgical recovery in individuals with cervical radiculopathy: a machine learning approach.

Scientific reports
Prognostic models play an important role in the clinical management of cervical radiculopathy (CR). No study has compared the performance of modern machine learning techniques, against more traditional stepwise regression techniques, when developing ...

Activity-based training with the Myosuit: a safety and feasibility study across diverse gait disorders.

Journal of neuroengineering and rehabilitation
BACKGROUND: Physical activity is a recommended part of treatment for numerous neurological and neuromuscular disorders. Yet, many individuals with limited mobility are not able to meet the recommended activity levels. Lightweight, wearable robots lik...

Automated Segmentation of Retinal Fluid Volumes From Structural and Angiographic Optical Coherence Tomography Using Deep Learning.

Translational vision science & technology
PURPOSE: We proposed a deep convolutional neural network (CNN), named Retinal Fluid Segmentation Network (ReF-Net), to segment retinal fluid in diabetic macular edema (DME) in optical coherence tomography (OCT) volumes.

US primary care in 2029: A Delphi survey on the impact of machine learning.

PloS one
OBJECTIVE: To solicit leading health informaticians' predictions about the impact of AI/ML on primary care in the US in 2029.