AIMC Topic: Middle Aged

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Integrated analysis of shared gene expression signatures and immune microenvironment heterogeneity in type 2 diabetes mellitus and colorectal cancer.

Scientific reports
Emerging evidence suggests a bidirectional relationship between colorectal cancer (CRC) and type 2 diabetes mellitus (T2DM), yet the shared molecular mechanisms and prognostic biomarkers remain poorly characterized. This study aimed to identify novel...

Machine learning to improve predictive performance of prehospital early warning scores.

Scientific reports
Early warning scores are used to assess acute patients' risk of being in a critical situation, allowing for early appropriate treatment, avoiding critical outcomes. The early warning scores use changes in vital signs to provide an assessment, however...

Machine learning analysis of kinematic movement features during functional tasks to discriminate chronic neck pain patients from asymptomatic controls.

Scientific reports
This study evaluated the discriminative potential of a machine learning model using movement features during functional tasks to distinguish between patients with non-traumatic chronic neck pain and asymptomatic controls. The study included patients ...

Proteomic risk scores for predicting common diseases using linear and neural network models in the UK biobank.

Scientific reports
Plasma proteomics provides a unique opportunity to enhance disease prediction by capturing protein expression patterns linked to diverse pathological processes. Leveraging data from 2,923 proteins measured in 53,030 UK Biobank participants, we develo...

Modeling the prediction of spontaneous rupture and bleeding in hepatocellular carcinoma via machine learning algorithms.

Scientific reports
This study aimed to identify the risk factors associated with spontaneous rupture and bleeding in hepatocellular carcinoma, establish a prediction model for spontaneous rupture bleeding via a machine learning algorithm, and validate and evaluate the ...

Automated classification of chondroid tumor using 3D U-Net and radiomics with deep features.

Scientific reports
Classifying chondroid tumors is an essential step for effective treatment planning. Recently, with the advances in computer-aided diagnosis and the increasing availability of medical imaging data, automated tumor classification using deep learning sh...

Identifying ovarian cancer with machine learning DNA methylation pattern analysis.

Scientific reports
The majority of patients with epithelial ovarian cancer (EOC) continue to be diagnosed at an advanced stage despite great advances in this disease treatment. To impact overall survival, we need better methods of EOC early diagnosis. We performed a ca...

A modified generative adversarial networks method for assisting the diagnosis of deep venous thrombosis complications in stroke patients.

Scientific reports
Discriminate deep vein thrombosis, one of the complications in early stroke patients, in order to assist in diagnosis. We have constructed a new method called ACWGAN by combining ACGAN and WGAN methods for data augmentation to to enhance the data of ...

Survival analysis for sepsis patients: A machine learning approach to feature selection and predictive modeling.

Scientific reports
Sepsis is a life-threatening condition that presents substantial challenges to healthcare and pharmacological management due to its high mortality rates and complex patient responses. Accurately predicting patient outcomes is essential for optimizing...

The effects of robot anthropomorphic characteristics on employees' anti-robot sabotage.

Scientific reports
Robot anthropomorphic characteristics have not only been widely manifested in production practices, but their positive effects on human-robot interaction have also been investigated and validated in academic research. Nonetheless, existing research h...