PURPOSE: Tumor-infiltrating lymphocytes (TILs) play a crucial role in host antitumor processes. High level of TILs is associated with better outcomes for patients. We aim to automatically quantify TILs without any nuclei annotation and further constr...
Non-coding RNAs (ncRNAs) play a crucial role in breast cancer progression, necessitating advanced computational approaches for precise disease classification. This study introduces a Deep Reinforcement Learning (DRL)-based framework for predicting nc...
BACKGROUND: The early prediction of lymph node positivity (LN+) after neoadjuvant chemotherapy (NAC) is crucial for optimizing individualized treatment strategies. This study aimed to integrate radiomic features and clinical biomarkers through machin...
Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive malignancy with complex molecular underpinnings. Hodgkin lymphoma (HL), another distinct cancer type, shares several biological characteristics with HNSCC, particularly regarding im...
Acute myeloid leukemia (AML) is a severe hematological malignancy characterized by high recurrence rates, especially in pediatric patients, highlighting the need for reliable prognostic markers. This study proposes methylation signatures associated w...
IEEE journal of biomedical and health informatics
May 6, 2025
Shock is a life-threatening condition characterized by generalized circulatory failure, which can have devastating consequences if not promptly treated. Thus, early prediction and continuous monitoring of physiological signs are essential for timely ...
BACKGROUND: Oral squamous cell carcinoma (OSCC) is one of the most common malignancies with poor clinical outcome. Regulatory T cells (Tregs) have a dual role in maintaining immune homeostasis and suppressing anti-tumor immunity. The role of Tregs re...
International journal of chronic obstructive pulmonary disease
May 6, 2025
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Comorbidities in patients with COPD significantly increase morbidity, mortality, and healthcare costs, posing a significant burden on the management o...
RATIONALE AND OBJECTIVES: Accurate risk stratification is critical for guiding personalized treatment in resectable pancreatic cancer (RPC). This retrospective study assessed the utility of habitat radiomics for predicting recurrence-free survival (R...
The forecasting of a patient's response to radiotherapy and the likelihood of experiencing harmful long-term health impacts would considerably enhance individual treatment plans. Due to the continuous exposure to radiation, cardiovascular disease and...
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