AIMC Topic: Troponin I

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Analytical Concordance of Diverse Point-of-Care and Central Laboratory Troponin I Assays.

The journal of applied laboratory medicine
BACKGROUND: Cardiac troponin I (cTnI) 99th percentile cutoffs, used in the diagnosis of acute myocardial infarction, are not standardized across cTnI assays. We compared 3 point-of-care (POC) and 1 central laboratory contemporary cTnI assays against ...

Effect of Health and Training on Ultrasensitive Cardiac Troponin in Marathon Runners.

The journal of applied laboratory medicine
PURPOSE: Cardiac troponin (cTn) is the gold standard biomarker for assessing cardiac damage. Previous studies have demonstrated increases in plasma cTn because of extreme exercise, including marathon running. We developed an easy-to-use, ultrasensiti...

Serum Troponin I levels among hypertensive Military Service Personnel at a Military Health Facility in Abuja, Nigeria.

Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria
Hypertension constitutes one of the major metabolic disease in Nigeria especially among military personnel and their families. Myocardial infarction and other cardiovascular diseases may occur in this group of patient due to uncontrolled or poorly co...

Mild troponin elevation in patients admitted to the emergency department with atrial fibrillation: 30-day post-discharge prognostic significance.

Internal and emergency medicine
Patients with atrial fibrillation (AF) often undergo troponin (Tn) testing in the emergency department (ED), but the clinical significance of mildly elevated values remains unclear. We evaluated short-term 30-day post-discharge outcomes in AF patient...

Electrochemiluminescent detection of cardiac troponin I by using soybean peroxidase labeled-antibody as signal amplifier.

Talanta
This work proposed an electrochemiluminescence (ECL) immunosensor for quantitative monitoring of cardiac troponin I (cTnI) in plasma with soybean peroxidase (SBP) labeled-antibody as signal amplifier. The ECL sandwich immunosensor was constructed by ...

Highly sensitive amperometric detection of cardiac troponin I using sandwich aptamers and screen-printed carbon electrodes.

Talanta
In this study, we developed a sandwich aptamer-based screen-printed carbon electrode (SPCE) using chronoamperometry for the detection of cardiac troponin I (cTnI), one of the promising biomarkers for acute myocardial infarction (AMI). Disposable thre...

Diagnosis of Acute Coronary Syndrome with a Support Vector Machine.

Journal of medical systems
Acute coronary syndrome (ACS) is a serious condition arising from an imbalance of supply and demand to meet myocardium's metabolic needs. Patients typically present with retrosternal chest pain radiating to neck and left arm. Electrocardiography (ECG...

Nanocomposites of gold nanoparticles and graphene oxide towards an stable label-free electrochemical immunosensor for detection of cardiac marker troponin-I.

Analytica chimica acta
A stable label-free amperometric immunosensor is presented based on gold nanoparticles and graphene oxide nanocomposites for detection of cardiac troponin-I in the early diagnosis of myocardial infarction. For designing of the sensing platform, first...

Renal impairment and outcome in patients with takotsubo cardiomyopathy.

The American journal of emergency medicine
OBJECTIVES: The objectives were to ascertain the prevalence of renal impairment among patients with a takotsubo cardiomyopathy (TTC) episode and whether clinical outcomes are related to renal function.