AIMC Topic: Biopsy

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Artificial intelligence-enhanced interpretation of kidney transplant biopsy: focus on rejection.

Current opinion in organ transplantation
PURPOSE OF REVIEW: The objective of this review is to provide an update on the application of artificial intelligence (AI) for the histological interpretation of kidney transplant biopsies.

GraftIQ: Hybrid multi-class neural network integrating clinical insight for multi-outcome prediction in liver transplant recipients.

Nature communications
Liver transplant recipients (LTRs) are at risk of graft injury, leading to cirrhosis and reduced survival. Liver biopsy, the diagnostic gold standard, is invasive and risky. We developed a hybrid multi-class neural network (NN) model, 'GraftIQ,' inte...

Bridging the gap: Evaluating ChatGPT-generated, personalized, patient-centered prostate biopsy reports.

American journal of clinical pathology
OBJECTIVE: The highly specialized language used in prostate biopsy pathology reports coupled with low rates of health literacy leave some patients unable to comprehend their medical information. Patients' use of online search engines can lead to misi...

Enhancing basal cell carcinoma classification in preoperative biopsies via transfer learning with weakly supervised graph transformers.

BMC medical imaging
BACKGROUND: Basal cell carcinoma (BCC) is the most common skin cancer, placing a significant burden on healthcare systems globally. Developing high-precision automated diagnostics requires large annotated datasets, which are costly and difficult to o...

Towards Optical Biopsy in Glioma Surgery.

International journal of molecular sciences
Currently, the focus of intraoperative imaging in brain tumor surgery is beginning to shift to optical methods such as optical coherence tomography (OCT), Raman spectroscopy, confocal laser endomicroscopy (CLE), and fluorescence lifetime imaging (FLI...

Evaluation of minor labial salivary gland focus score in Sjögren's disease using deep learning: a tool for more efficient diagnosis and future tissue biomarker discovery.

Journal of autoimmunity
BACKGROUND: Sjögren's Disease (SjD) is histopathologically characterized by focal sialadenitis in minor labial salivary gland biopsies (mLSGB), which is evaluated by utilizing the focus score (FS). Focus score ≥1 identification is a critical step of ...

Utility of AI digital pathology as an aid for pathologists scoring fibrosis in MASH.

Journal of hepatology
BACKGROUND & AIMS: Intra and inter-pathologist variability poses a significant challenge in metabolic dysfunction-associated steatohepatitis (MASH) biopsy evaluation, leading to suboptimal selection of patients and confounded assessment of histologic...

Deep Learning-Based Classification of Early-Stage Mycosis Fungoides and Benign Inflammatory Dermatoses on H&E-Stained Whole-Slide Images: A Retrospective, Proof-of-Concept Study.

The Journal of investigative dermatology
The diagnosis of early-stage mycosis fungoides (MF) is challenging owing to shared clinical and histopathological features with benign inflammatory dermatoses. Recent evidence has shown that deep learning (DL) can assist pathologists in cancer classi...

Validation of a Digital Pathology-Based Multimodal Artificial Intelligence Biomarker in a Prospective, Real-World Prostate Cancer Cohort Treated with Prostatectomy.

Clinical cancer research : an official journal of the American Association for Cancer Research
PURPOSE: A multimodal artificial intelligence (MMAI) biomarker was developed using clinical trial data from North American men with localized prostate cancer treated with definitive radiation, using biopsy digital pathology images and key clinical in...

Artificial intelligence-aided optical biopsy improves the diagnosis of esophageal squamous neoplasm.

World journal of gastroenterology
BACKGROUND: Early detection of esophageal squamous neoplasms (ESN) is essential for improving patient prognosis. Optical diagnosis of ESN remains challenging. Probe-based confocal laser endomicroscopy (pCLE) enables accurate histological observation...