Current opinion in organ transplantation
Jun 1, 2025
PURPOSE OF REVIEW: The objective of this review is to provide an update on the application of artificial intelligence (AI) for the histological interpretation of kidney transplant biopsies.
Liver transplant recipients (LTRs) are at risk of graft injury, leading to cirrhosis and reduced survival. Liver biopsy, the diagnostic gold standard, is invasive and risky. We developed a hybrid multi-class neural network (NN) model, 'GraftIQ,' inte...
American journal of clinical pathology
May 17, 2025
OBJECTIVE: The highly specialized language used in prostate biopsy pathology reports coupled with low rates of health literacy leave some patients unable to comprehend their medical information. Patients' use of online search engines can lead to misi...
BACKGROUND: Basal cell carcinoma (BCC) is the most common skin cancer, placing a significant burden on healthcare systems globally. Developing high-precision automated diagnostics requires large annotated datasets, which are costly and difficult to o...
International journal of molecular sciences
May 9, 2025
Currently, the focus of intraoperative imaging in brain tumor surgery is beginning to shift to optical methods such as optical coherence tomography (OCT), Raman spectroscopy, confocal laser endomicroscopy (CLE), and fluorescence lifetime imaging (FLI...
BACKGROUND: Sjögren's Disease (SjD) is histopathologically characterized by focal sialadenitis in minor labial salivary gland biopsies (mLSGB), which is evaluated by utilizing the focus score (FS). Focus score ≥1 identification is a critical step of ...
BACKGROUND & AIMS: Intra and inter-pathologist variability poses a significant challenge in metabolic dysfunction-associated steatohepatitis (MASH) biopsy evaluation, leading to suboptimal selection of patients and confounded assessment of histologic...
The Journal of investigative dermatology
May 1, 2025
The diagnosis of early-stage mycosis fungoides (MF) is challenging owing to shared clinical and histopathological features with benign inflammatory dermatoses. Recent evidence has shown that deep learning (DL) can assist pathologists in cancer classi...
Clinical cancer research : an official journal of the American Association for Cancer Research
Apr 14, 2025
PURPOSE: A multimodal artificial intelligence (MMAI) biomarker was developed using clinical trial data from North American men with localized prostate cancer treated with definitive radiation, using biopsy digital pathology images and key clinical in...
BACKGROUND: Early detection of esophageal squamous neoplasms (ESN) is essential for improving patient prognosis. Optical diagnosis of ESN remains challenging. Probe-based confocal laser endomicroscopy (pCLE) enables accurate histological observation...
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