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Cell Membrane

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Effect of Cholesterol-loaded Cyclodextrin on Membrane and Acrosome Status of Hariana Bull Sperm during Cryopreservation.

Cryo letters
BACKGROUND: The membrane and acrosomal integrity of sperm play a vital role in fertilization process; however they are compromised upon cryopreservation.

ACTIVITY OF BLACKCURRANT AND CHOKEBERRY EXTRACTS AND TWO MAJOR CYANIDIN GLYCOSIDES AGAINST LIPID MEMBRANE OXIDATION AND THEIR BINDING PROPERTIES TO ALBUMIN.

Acta poloniae pharmaceutica
The purpose of this study was to explain how extracts from chokeberry and blackcurrant interact with the lipid phase of biological membrane and with human albumin - the main protein of blood. Aiming at better understanding of the observed biological ...

Classifying the molecular functions of Rab GTPases in membrane trafficking using deep convolutional neural networks.

Analytical biochemistry
Deep learning has been increasingly used to solve a number of problems with state-of-the-art performance in a wide variety of fields. In biology, deep learning can be applied to reduce feature extraction time and achieve high levels of performance. I...

Cell-Like Micromotors.

Accounts of chemical research
In the past decade, versatile micro- and nanosized machines have emerged as active agents for large-scale detoxification, sensing, microfabrication, and many other promising applications. Micromachines have also been envisioned as the next advancemen...

Levels and building blocks-toward a domain granularity framework for the life sciences.

Journal of biomedical semantics
BACKGROUND: With the emergence of high-throughput technologies, Big Data and eScience, the use of online data repositories and the establishment of new data standards that require data to be computer-parsable become increasingly important. As a conse...

Hindmarsh-Rose neuron model with memristors.

Bio Systems
We analyze single and coupled Hindmarsh-Rose neurons in the presence of a time varying electromagnetic field which results from the exchange of ions across the membrane. Memristors are used to model the relation between magnetic flux of the electroma...

Machine Learning Based Real-Time Image-Guided Cell Sorting and Classification.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
Cell classification based on phenotypical, spatial, and genetic information greatly advances our understanding of the physiology and pathology of biological systems. Technologies derived from next generation sequencing and fluorescent activated cell ...

Automated segmentation of cell membranes to evaluate HER2 status in whole slide images using a modified deep learning network.

Computers in biology and medicine
The uncontrollable growth of cells in the breast tissue causes breast cancer which is the second most common type of cancer affecting women in the United States. Normally, human epidermal growth factor receptor 2 (HER2) proteins are responsible for t...

Novel machine learning application for prediction of membrane insertion potential of cell-penetrating peptides.

International journal of pharmaceutics
Cell-penetrating peptides (CPPs) are often used as transporter systems to deliver various therapeutic agents into the cell. We developed a novel machine learning application which can quantitatively screen the insertion/interaction potential of vario...