AIMC Topic: Disease Progression

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Multi-task deep learning-based survival analysis on the prognosis of late AMD using the longitudinal data in AREDS.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Age-related macular degeneration (AMD) is the leading cause of vision loss. Some patients experience vision loss over a delayed timeframe, others at a rapid pace. Physicians analyze time-of-visit fundus photographs to predict patient risk of developi...

IDNetwork: A deep illness-death network based on multi-state event history process for disease prognostication.

Statistics in medicine
Multi-state models can capture the different patterns of disease evolution. In particular, the illness-death model is used to follow disease progression from a healthy state to an intermediate state of the disease and to a death-related final state. ...

Dynamic Bayesian networks for prediction of health status and treatment effect in patients with chronic lymphocytic leukemia.

Scientific reports
Chronic lymphocytic leukemia (CLL) is the most common blood cancer in adults. The course of CLL and patients' response to treatment are varied. This variability makes it difficult to select the most appropriate treatment regimen and predict the progr...

A Deep Learning Approach to Predicting Disease Progression in Multiple Sclerosis Using Magnetic Resonance Imaging.

Investigative radiology
OBJECTIVES: Magnetic resonance imaging (MRI) is an important tool for diagnosis and monitoring of disease course in multiple sclerosis (MS). However, its prognostic value for predicting disease worsening is still being debated. The aim of this study ...

Disease Progression Detection via Deep Sequence Learning of Successive Radiographic Scans.

International journal of environmental research and public health
The highly rapid spread of the current pandemic has quickly overwhelmed hospitals all over the world and motivated extensive research to address a wide range of emerging problems. The unforeseen influx of COVID-19 patients to hospitals has made it in...

Alteration of the corpus callosum in patients with Alzheimer's disease: Deep learning-based assessment.

PloS one
BACKGROUND: Several studies have reported changes in the corpus callosum (CC) in Alzheimer's disease. However, the involved region differed according to the study population and study group. Using deep learning technology, we ensured accurate analysi...

ResGANet: Residual group attention network for medical image classification and segmentation.

Medical image analysis
In recent years, deep learning technology has shown superior performance in different fields of medical image analysis. Some deep learning architectures have been proposed and used for computational pathology classification, segmentation, and detecti...

Machine learning of genomic features in organotropic metastases stratifies progression risk of primary tumors.

Nature communications
Metastatic cancer is associated with poor patient prognosis but its spatiotemporal behavior remains unpredictable at early stage. Here we develop MetaNet, a computational framework that integrates clinical and sequencing data from 32,176 primary and ...

Predictive value of ATN biomarker profiles in estimating disease progression in Alzheimer's disease dementia.

Alzheimer's & dementia : the journal of the Alzheimer's Association
We aimed to evaluate the value of ATN biomarker classification system (amyloid beta [A], pathologic tau [T], and neurodegeneration [N]) for predicting conversion from mild cognitive impairment (MCI) to dementia. In a sample of people with MCI (n = 41...