AIMC Topic: Kaplan-Meier Estimate

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Long-term oncologic and functional outcomes following robot-assisted radical cystectomy and intracorporeal Padua ileal bladder: results from a single high-volume center.

World journal of urology
PURPOSE: To report long-term oncologic and functional outcomes of a large consecutive single center series of Robot-assisted radical cystectomy (RARC)- intracorporeal (IC) Urinary Diversion (UD), identifying their predicting factors.

Unsupervised learning of cross-modal mappings in multi-omics data for survival stratification of gastric cancer.

Future oncology (London, England)
This study presents a survival stratification model based on multi-omics integration using bidirectional deep neural networks (BiDNNs) in gastric cancer. Based on the survival-related representation features yielded by BiDNNs through integrating tr...

Machine learning of genomic features in organotropic metastases stratifies progression risk of primary tumors.

Nature communications
Metastatic cancer is associated with poor patient prognosis but its spatiotemporal behavior remains unpredictable at early stage. Here we develop MetaNet, a computational framework that integrates clinical and sequencing data from 32,176 primary and ...

Predictive value of red blood cell distribution width in septic shock patients with thrombocytopenia: A retrospective study using machine learning.

Journal of clinical laboratory analysis
BACKGROUND: Sepsis-associated thrombocytopenia (SAT) is common in critical patients and results in the elevation of mortality. Red cell distribution width (RDW) can reflect body response to inflammation and oxidative stress. We try to investigate the...

Deep learning-based virtual cytokeratin staining of gastric carcinomas to measure tumor-stroma ratio.

Scientific reports
The tumor-stroma ratio (TSR) determined by pathologists is subject to intra- and inter-observer variability. We aimed to develop a computational quantification method of TSR using deep learning-based virtual cytokeratin staining algorithms. Patients ...

Combining multi-site magnetic resonance imaging with machine learning predicts survival in pediatric brain tumors.

Scientific reports
Brain tumors represent the highest cause of mortality in the pediatric oncological population. Diagnosis is commonly performed with magnetic resonance imaging. Survival biomarkers are challenging to identify due to the relatively low numbers of indiv...

Personalised Medicine for Colorectal Cancer Using Mechanism-Based Machine Learning Models.

International journal of molecular sciences
Gaining insight into the mechanisms of signal transduction networks (STNs) by using critical features from patient-specific mathematical models can improve patient stratification and help to identify potential drug targets. To achieve this, these mod...

Deep learning-based gene selection in comprehensive gene analysis in pancreatic cancer.

Scientific reports
The selection of genes that are important for obtaining gene expression data is challenging. Here, we developed a deep learning-based feature selection method suitable for gene selection. Our novel deep learning model includes an additional feature-s...