Longitudinal serological proteomic dynamics during antiviral therapy (AVT) in chronic hepatitis B (CHB) patients with liver fibrosis remain poorly characterized. Here, using four-dimensional data-independent acquisition mass spectrometry (4D-DIA-MS),...
Immunogenic cell death (ICD) is capable of activating both innate and adaptive immune responses. In this study, we aimed to develop an ICD-related signature in glioma patients and facilitate the assessment of their prognosis and drug sensitivity. Con...
Spinal nerve sheath tumors are slow-growing neoplasms that arise from Schwann cell lineage and encompass schwannomas, neurofibromas, hybrid nerve sheath tumors, and malignant peripheral nerve sheath tumors. These lesions most commonly present as intr...
This study compared an automated deep learning algorithm with certified human graders from the Vienna Reading Center (VRC) in identifying intra- (IRF) and subretinal fluid (SRF) in OCT scans of patients treated for neovascular age-related macular deg...
The relationship between interleukin-22 and clinical characteristics of patients with inflammatory bowel disease is uncertain. We sought to determine whether plasma interleukin-22 concentrations are associated with disease activity in a large populat...
OBJECTIVES: This study aims to develop a deep learning algorithm (DLA) using the InceptionV3 architecture for effective diabetic peripheral neuropathy (DPN) screening via corneal confocal microscopy (CCM) images.
BACKGROUND: Artificial intelligence-powered chatbots (AI-PCs) are increasingly integrated into educational settings, including health care disciplines. Despite their potential to enhance learning, limited research has investigated physiotherapy (PT) ...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Aug 15, 2025
Vascular aging-related remodeling is a common pathological basis for many chronic diseases, so early detection of physical arterial aging is important for their prevention and control. Existing staining methods can only analyze a limited number of ti...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Aug 15, 2025
Diabetic encephalopathy is a progressive complication of type 2 diabetes, yet its region-specific biochemical changes remain unclear. In this study, we applied Fourier Transform Infrared Microspectroscopy (FTIRM) to assess metabolic alterations in th...
BACKGROUND: This study aims to apply a semi-supervised machine learning approach for classifying major depressive disorder (MDD) patients into more homogeneous cognitive subtypes based on multidimensional cognitive profiles, and to perform multimodal...
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