AIMC Topic: Neoplasm Staging

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Prediction of Occult Invasive Disease in Ductal Carcinoma in Situ Using Deep Learning Features.

Journal of the American College of Radiology : JACR Feb 2, 2018
PURPOSE: The aim of this study was to determine whether deep features extracted from digital mammograms using a pretrained deep convolutional neural network are prognostic of occult invasive disease for patients with ductal carcinoma in situ (DCIS) o...
Humans Neural Networks, Computer Prognosis Retrospective Studies Female Mammography Neoplasm Staging Carcinoma, Intraductal, Noninfiltrating Monte Carlo Method Biopsy, Large-Core Needle Carcinoma in Situ Aged Adult Breast Neoplasms Middle Aged Deep Learning
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Prognostic values of the integrated model incorporating the volume of metastatic regional cervical lymph node and pretreatment serum Epstein-Barr virus DNA copy number in predicting distant metastasis in patients with N1 nasopharyngeal carcinoma.

Chinese journal of cancer Dec 29, 2017
BACKGROUND: According to the 7th edition of the American Joint Committee on Cancer (AJCC) staging system, over 50% of patients with nasopharyngeal carcinoma (NPC) have N1 disease at initial diagnosis. However, patients with N1 NPC are relatively unde...
Survival Analysis Nasopharyngeal Carcinoma Nasopharyngeal Neoplasms Humans Epstein-Barr Virus Infections Herpesvirus 4, Human Lymphatic Metastasis DNA Copy Number Variations Neoplasm Staging Prognosis Female Male ROC Curve DNA, Viral
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HCV nonstructural protein 4 is associated with aggressiveness features of breast cancer.

Breast cancer (Tokyo, Japan) Dec 28, 2017
BACKGROUND: Hepatitis C virus (HCV) has the lymphotropic feature that is supposed to be the reason of related extrahepatic manifestation. HCV viral oncoproteins may participate in the regulation of some gene expression that has been implicated in tum...
Middle Aged Disease Progression Incidence Gene Expression Regulation, Neoplastic Enzyme-Linked Immunosorbent Assay Carcinogenesis Hepacivirus Humans Egypt Hepatitis C Female Neoplasm Staging Viral Nonstructural Proteins Aged Neoplasm Grading Mucin-1 Adult Fibronectins Hepatitis C Antibodies Breast Neoplasms
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The utility of sentinel lymph node mapping in the management of endometrial atypical hyperplasia.

Gynecologic oncology Dec 28, 2017
OBJECTIVES: To determine the risk of endometrial cancer (EC) and lymph node involvement in patients with a preoperative diagnosis of "AH-only" versus "AH - cannot rule out carcinoma" and to study the value of SLN mapping.
Lymph Node Excision Predictive Value of Tests Neoplasm Staging Neoplasm Grading Pelvis Endometrial Neoplasms CA-125 Antigen Carcinoma, Endometrioid Endometrial Hyperplasia Myometrium Humans Sentinel Lymph Node Biopsy Female Aged Aged, 80 and over Adult Sensitivity and Specificity Middle Aged Membrane Proteins Lymphatic Metastasis Neoplasm Invasiveness
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Overexpression of EMMPRIN is associated with lymph node metastasis and advanced stage of non-small cell lung cancer: a retrospective study.

BMC pulmonary medicine Dec 28, 2017
BACKGROUND: Previous studies show that overexpression of EMMPRIN involved in the malignant biological behavior of tumors. This investigation was to disclose the expression status of EMMPRIN in non-small cell lung cancer (NSCLC) and its clinical value...
Humans Retrospective Studies Female Neoplasm Staging Immunohistochemistry Up-Regulation Basigin Risk Factors Lung Neoplasms Gene Expression Regulation, Neoplastic Biomarkers, Tumor Lymph Nodes Male Carcinoma, Non-Small-Cell Lung Middle Aged Lymphatic Metastasis ROC Curve
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Artificial intelligence may help in predicting the need for additional surgery after endoscopic resection of T1 colorectal cancer.

Endoscopy Dec 22, 2017
BACKGROUND AND STUDY AIMS: Decisions concerning additional surgery after endoscopic resection of T1 colorectal cancer (CRC) are difficult because preoperative prediction of lymph node metastasis (LNM) is problematic. We investigated whether artificia...
Heuristics Japan Unnecessary Procedures Middle Aged Risk Assessment Humans Models, Theoretical Artificial Intelligence Lymphatic Metastasis Prognosis Neoplasm Staging Female Aged Endoscopy Sensitivity and Specificity Colorectal Neoplasms Diagnostic Errors Male
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MRI radiomics analysis of molecular alterations in low-grade gliomas.

International journal of computer assisted radiology and surgery Dec 21, 2017
PURPOSE: Low-grade gliomas (LGG) are classified into three distinct groups based on their IDH1 mutation and 1p/19q codeletion status, each of which is associated with a different clinical expression. The genomic sub-classification of LGG requires tum...
Female Aged Brain Neoplasms Male Middle Aged Glioma Magnetic Resonance Imaging Neoplasm Staging Neurosurgical Procedures Cerebral Cortex Preoperative Period Humans Machine Learning
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Prediction of organ-confined disease after robot-assisted radical prostatectomy in patients with clinically locally-advanced prostate cancer.

Asian journal of surgery Dec 20, 2017
BACKGROUND: Little is known about the preoperative predictive factors that could identify subsets of favorable patients who can be possibly cured with robot-assisted radical prostatectomy (RARP) alone in locally advanced prostate cancer (LAPCa). Our ...
Humans Forecasting Biomarkers Prognosis Retrospective Studies Aged Male Middle Aged Biopsy, Large-Core Needle Prostate-Specific Antigen Cohort Studies Neoplasm Grading Logistic Models Robotic Surgical Procedures Neoadjuvant Therapy Prostatectomy Prostatic Neoplasms Preoperative Care Neoplasm Staging
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Post prostatectomy outcomes of patients with high-risk prostate cancer treated with neoadjuvant androgen blockade.

Prostate cancer and prostatic diseases Dec 20, 2017
BACKGROUND: Patients with high-risk prostate cancer have an increased likelihood of experiencing a relapse following radical prostatectomy (RP). We previously conducted three neoadjuvant androgen-deprivation therapy (ADT) trials prior to RP in unfavo...
Neoadjuvant Therapy Follow-Up Studies Multicenter Studies as Topic Randomized Controlled Trials as Topic Prostatic Neoplasms Humans Aged Male Middle Aged Treatment Outcome Disease-Free Survival Prostatectomy Kallikreins Neoplasm Staging Prostate-Specific Antigen Prostate Androgen Antagonists Neoplasm Recurrence, Local
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Multi-Objective Optimization Algorithm to Discover Condition-Specific Modules in Multiple Networks.

Molecules (Basel, Switzerland) Dec 14, 2017
The advances in biological technologies make it possible to generate data for multiple conditions simultaneously. Discovering the condition-specific modules in multiple networks has great merit in understanding the underlying molecular mechanisms of ...
Gene Expression Regulation Computational Biology Signal Transduction Humans Cell Line Neoplasm Staging Neural Networks, Computer Models, Biological Algorithms Biomarkers Breast Neoplasms Gene Expression Profiling Gene Regulatory Networks
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