AIMC Topic: Pancreatic Neoplasms

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Pancreatic gross tumor volume contouring on computed tomography (CT) compared with magnetic resonance imaging (MRI): Results of an international contouring conference.

Practical radiation oncology Nov 29, 2017
PURPOSE: Accurate identification of the gross tumor volume (GTV) in pancreatic adenocarcinoma is challenging. We sought to understand differences in GTV delineation using pancreatic computed tomography (CT) compared with magnetic resonance imaging (M...
Magnetic Resonance Imaging Humans Pancreatic Neoplasms Tomography, X-Ray Computed Aged Male
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Nano-biotinylated liposome-based immunoassay for the ultrasensitive detection of protein biomarker in urine.

Talanta Nov 21, 2017
With the development of proteomics and the continuous discovery of biomarkers of trace proteins, it is important to accurately quantify low abundance protein, especially in urine for clinical diagnostics. In this paper, we reported a novel nano-bioti...
Biomarkers, Tumor Liposomes Nucleic Acid Amplification Techniques Biotinylation Pancreatic Neoplasms 1,2-Dipalmitoylphosphatidylcholine Humans DNA Lithostathine Limit of Detection Reproducibility of Results Immunoassay Cholesterol Carcinoma, Pancreatic Ductal
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Neural network dose models for knowledge-based planning in pancreatic SBRT.

Medical physics Nov 1, 2017
PURPOSE: Stereotactic body radiation therapy (SBRT) for pancreatic cancer requires a skillful approach to deliver ablative doses to the tumor while limiting dose to the highly sensitive duodenum, stomach, and small bowel. Here, we develop knowledge-b...
Radiotherapy Planning, Computer-Assisted Radiation Dosage Humans Radiotherapy Dosage Neural Networks, Computer Radiosurgery Pancreatic Neoplasms Normal Distribution
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Computer-assisted cytologic diagnosis in pancreatic FNA: An application of neural networks to image analysis.

Cancer cytopathology Sep 8, 2017
BACKGROUND: Fine-needle aspiration (FNA) biopsy is an accurate method for the diagnosis of solid pancreatic masses. However, a significant number of cases still pose a diagnostic challenge. The authors have attempted to design a computer model to aid...
Carcinoma, Pancreatic Ductal Humans Pancreatectomy Bile Duct Neoplasms Neural Networks, Computer Pancreas Computer Simulation Adenocarcinoma Reproducibility of Results Diagnosis, Differential Diagnosis, Computer-Assisted Pancreatic Neoplasms Image Processing, Computer-Assisted Cytodiagnosis Biopsy, Fine-Needle
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An Evaluation of Artificial Neural Networks in Predicting Pancreatic Cancer Survival.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract Aug 3, 2017
OBJECTIVE: This study aims to evaluate the development of an artificial neural network (ANN) method for predicting the survival likelihood of pancreatic adenocarcinoma patients. The ANN predictive model should produce results with a 90% sensitivity.
Neural Networks, Computer Prospective Studies Female Aged Humans Pancreatic Neoplasms Likelihood Functions Sensitivity and Specificity Male Middle Aged Adenocarcinoma Aged, 80 and over Young Adult Adult Survival Rate
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Impact of chromogranin A, differentiation, and mitoses in nonfunctional pancreatic neuroendocrine tumors ≤ 2 cm.

The Journal of surgical research Dec 29, 2016
BACKGROUND: Small pancreatic neuroendocrine tumors (PNETs) are a unique subset of pancreatic neoplasms. Chromogranin A (CgA) levels, mitotic rate, and histologic differentiation are often used to characterize PNET behavior. This study evaluates the i...
Humans Databases, Factual Chromogranin A Prognosis Mitosis Retrospective Studies Female Adult Neuroendocrine Tumors Neoplasm Staging Aged Biomarkers, Tumor Survival Analysis Aged, 80 and over Adolescent Male Multivariate Analysis Young Adult Logistic Models Middle Aged Propensity Score Pancreatic Neoplasms Cell Differentiation
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Analysis of Important Gene Ontology Terms and Biological Pathways Related to Pancreatic Cancer.

BioMed research international Nov 9, 2016
Pancreatic cancer is a serious disease that results in more than thirty thousand deaths around the world per year. To design effective treatments, many investigators have devoted themselves to the study of biological processes and mechanisms underlyi...
Gene Ontology Humans Signal Transduction Databases, Genetic Pancreatic Neoplasms
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Indications, technique, and results of robotic pancreatoduodenectomy.

Updates in surgery Sep 10, 2016
Robotic assistance improves surgical dexterity in minimally invasive operations, especially when fine dissection and multiple sutures are required. As such, robotic assistance could be rewarding in the setting of robotic pancreatoduodenectomy (RPD). ...
Robotics Laparoscopy Italy Feasibility Studies Treatment Outcome Follow-Up Studies Operative Time Pancreatic Neoplasms Pancreas Humans Pancreaticoduodenectomy Retrospective Studies Male Conversion to Open Surgery Female Middle Aged Postoperative Complications Incidence
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Literature-based knowledgebase of pancreatic cancer gene to prioritize the key genes and pathways.

Journal of genetics and genomics = Yi chuan xue bao Jul 9, 2016
Oncogenes Humans Pancreatic Neoplasms Knowledge Bases
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Monitoring vascular normalization induced by antiangiogenic treatment with (18)F-fluoromisonidazole-PET.

Molecular oncology Dec 22, 2015
BACKGROUND: Rationalization of antiangiogenics requires biomarkers. Vascular re-normalization is one widely accepted mechanism of action for this drug class. The interstitium of tumors with abnormal vasculature is hypoxic. We sought to track vascular...
Humans Female Breast Neoplasms Animals Cell Line, Tumor Pancreas Cell Hypoxia Breast Antimetabolites, Antineoplastic Fluorine Radioisotopes Mice Positron-Emission Tomography Deoxycytidine Angiogenesis Inhibitors Benzimidazoles Mice, Nude Gemcitabine Quinolones Pancreatic Neoplasms Misonidazole Neovascularization, Pathologic
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