AIMC Topic: Rats, Wistar
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Unsupervised machine learning using an imaging mass spectrometry dataset automatically reassembles grey and white matter.
Scientific reports
Sep 13, 2019
Current histological and anatomical analysis techniques, including fluorescence in situ hybridisation, immunohistochemistry, immunofluorescence, immunoelectron microscopy and fluorescent fusion protein, have revealed great distribution diversity of m...
A non-linear mathematical model using optical sensor to predict heart decellularization efficacy.
Scientific reports
Aug 21, 2019
One of the main problems of the decellularization technique is the subjectivity of the final evaluation of its efficacy in individual organs. This problem can result in restricted cell repopulation reproducibility and worse responses to transplant ti...
Comparison between two programs for image analysis, machine learning and subsequent classification.
Tissue & cell
Mar 27, 2019
In the early 1950s, flow cytometry was developed as the first method for automated quantitative cellular analysis. In the early 1990s, the first equipment for image cytometry (laser scanning cytometry, LSC) became commercially available. As flow cyto...
Neuroprotective role of 6-Gingerol-rich fraction of Zingiber officinale (Ginger) against acrylonitrile-induced neurotoxicity in male Wistar rats.
Journal of basic and clinical physiology and pharmacology
Dec 22, 2018
Background Acrylonitrile (AN) is a neurotoxin that is widely used to manufacture synthetic fibres, plastics and beverage containers. Recently, we reported the ameliorative role of 6-gingerol-rich fraction from Zingiber officinale (Ginger, GRF) on the...
Zingiber officinale
Glutathione Transferase
Glutathione
Oxidative Stress
Acrylonitrile
Neuroprotection
Antioxidants
Cerebral Cortex
Catalase
Tumor Necrosis Factor-alpha
Plant Extracts
Lipid Peroxidation
Fatty Alcohols
Rats, Wistar
Catechols
Interleukin-6
Nitric Oxide
Rats
Glutathione Peroxidase
Animals
Malondialdehyde
Male
Superoxide Dismutase
Inflammation
Low-Concentration Oxygen/Ozone Treatment Attenuated Radiculitis and Mechanical Allodynia via PDE2A-cAMP/cGMP-NF-B/p65 Signaling in Chronic Radiculitis Rats.
Pain research & management
Dec 13, 2018
BACKGROUND: Oxygen/ozone therapy is a minimally invasive technique for the treatment of radiculitis from lumbar disc herniation. This study aimed at investigating whether intrathecal administration of low-concentration oxygen/ozone could attenuate ch...
Seasonal Variation in Essential Oils Composition and the Biological and Pharmaceutical Protective Effects of Leaves Grown in Tunisia.
BioMed research international
Dec 9, 2018
This research assessed the seasonal variation of the chemical composition and antibacterial and anticholinesterase activities of essential oils extracted from leaves. The leaves organic fractions were also investigated for their biological activitie...
Novel indolizine derivatives lowers blood glucose levels in streptozotocin-induced diabetic rats: A histopathological approach.
Pharmacological reports : PR
Nov 28, 2018
BACKGROUND: Diabetes mellitus is a deadly disorder in human which induce chronic complications. The streptozotocin (STZ)-induced diabetes in rat is the most common animal model of human diabetes. The present study investigated the effects of novel in...
Metabolomics predicts the pharmacological profile of new psychoactive substances.
Journal of psychopharmacology (Oxford, England)
Nov 19, 2018
BACKGROUND: The unprecedented proliferation of new psychoactive substances (NPS) threatens public health and challenges drug policy. Information on NPS pharmacology and toxicity is, in most cases, unavailable or very limited and, given the large numb...
Effect of the in vitro gastrointestinal digestion on free-phenolic compounds and mono/oligosaccharides from Moringa oleifera leaves: Bioaccessibility, intestinal permeability and antioxidant capacity.
Food research international (Ottawa, Ont.)
Nov 10, 2018
Moringa oleifera is a plant recognized for its compounds such as dietary fiber (oligosaccharides, amongst others) and polyphenols, with biological activities. These properties depend on bioactive compounds (BC) interactions with food matrix/digestion...
Hypertonic Saline Modulates Heart Function and Myocardial Inflammatory Alterations in Brain-Dead Rats.
The Journal of surgical research
Oct 23, 2018
BACKGROUND: Brain death (BD) in potential organ donors is responsible for hemodynamic instability and organ hypoperfusion, leading to myocardial dysfunction. Hypertonic saline (HS) is a volume expander with positive effects on hemodynamics and immuno...
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