AIMC Topic: Triglycerides

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Enzymatic preparation of "functional oil" rich in feruloylated structured lipids with solvent-free ultrasound pretreatment.

Food chemistry Dec 19, 2017
In this study, a series of functional oils rich in feruloylated structured lipids (FSLs) was prepared by enzymatic transesterification of ethyl ferulate (EF) with triglycerides under ultrasound pretreatment. A conversion of more than 92.7% and contro...
Esterification Fatty Acids Solvents Ultrasonics Lipase Antioxidants Triglycerides Caffeic Acids Plant Oils Lipids Kinetics
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Circulating triacylglycerols but not pancreatic fat associate with insulin secretion in healthy humans.

Metabolism: clinical and experimental Dec 19, 2017
BACKGROUND: Loss of adequate insulin secretion for the prevailing insulin resistance is critical for the development of type 2 diabetes and has been suggested to result from circulating lipids (triacylglycerols [TG] or free fatty acids) and/or adipoc...
Humans Female Aged Male Middle Aged Insulin Fatty Acids, Nonesterified Insulin Resistance Triglycerides Lipids Insulin Secretion Adiponectin Insulin-Secreting Cells
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l-Carnosine supplementation attenuated fasting glucose, triglycerides, advanced glycation end products, and tumor necrosis factor-α levels in patients with type 2 diabetes: a double-blind placebo-controlled randomized clinical trial.

Nutrition research (New York, N.Y.) Nov 17, 2017
Considering the pathologic importance of metabolic disturbances, advanced glycation end products (AGEs), and chronic inflammation in diabetes mellitus and ameliorating potentials of l-carnosine in hampering these detritions and because these effects ...
Double-Blind Method Body Composition Glycated Hemoglobin Arginine Triglycerides Humans Middle Aged Glycation End Products, Advanced Lysine Tumor Necrosis Factor-alpha Carnosine Fasting Female Blood Glucose Adult Diabetes Mellitus, Type 2 Male Dietary Supplements Adipose Tissue
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Laboratory parameter-based machine learning model for excluding non-alcoholic fatty liver disease (NAFLD) in the general population.

Alimentary pharmacology & therapeutics Jun 6, 2017
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) affects 20%-40% of the general population in developed countries and is an increasingly important cause of hepatocellular carcinoma. Electronic medical records facilitate large-scale epidemiologic...
Humans Machine Learning Female Logistic Models Non-alcoholic Fatty Liver Disease Anthropometry Alanine Transaminase Lipoproteins, HDL Triglycerides Adult Sensitivity and Specificity Cross-Sectional Studies Male Middle Aged ROC Curve
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Prediction of Incident Diabetes in the Jackson Heart Study Using High-Dimensional Machine Learning.

PloS one Oct 11, 2016
Statistical models to predict incident diabetes are often based on limited variables. Here we pursued two main goals: 1) investigate the relative performance of a machine learning method such as Random Forests (RF) for detecting incident diabetes in ...
Triglycerides Black or African American Demography Glycated Hemoglobin Leptin Waist Circumference Cholesterol, HDL Anthropometry Adiponectin Biomarkers Blood Glucose Humans Female Incidence Machine Learning Aged Diabetes Mellitus, Type 2 Adult Models, Theoretical Male Follow-Up Studies Middle Aged C-Reactive Protein
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Adaptations to excess choline in insulin resistant and Pcyt2 deficient skeletal muscle.

Biochemistry and cell biology = Biochimie et biologie cellulaire Sep 6, 2016
It was hypothesized that choline supplementation in insulin resistant (IR) CTP:phosphoethanolamine cytidylyltransferase deficient (Pcyt2) mice would ameliorate muscle function by remodeling glucose and fatty acid (FA) metabolism. Pcyt2 mice either re...
fas Receptor Triglycerides Microtubule-Associated Proteins Glucose Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha Fatty Acids Carnitine O-Palmitoyltransferase Stearoyl-CoA Desaturase Administration, Oral Diacylglycerol O-Acyltransferase Lipogenesis Choline Insulin Receptor Substrate Proteins Adaptation, Physiological Gene Expression Regulation Animals Organic Cation Transport Proteins PPAR alpha Mice RNA Nucleotidyltransferases Insulin Resistance Sterol Regulatory Element Binding Protein 1 Signal Transduction Muscle, Skeletal Mice, Knockout
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Serum 25-hydroxyvitamin D and metabolic syndrome in a Japanese working population: The Furukawa Nutrition and Health Study.

Nutrition (Burbank, Los Angeles County, Calif.) Mar 16, 2016
OBJECTIVE: Increasing evidence has suggested a protective role of vitamin D on metabolic syndrome (MetS). However, studies addressing this issue are limited in Asia and it remains unclear whether calcium could modify the association. We examined the ...
Vitamin D Deficiency Metabolic Syndrome Blood Pressure Cholesterol Asian People Japan Waist Circumference Nutritional Status Multivariate Analysis Triglycerides Calcium, Dietary Multilevel Analysis Prevalence Adolescent Blood Glucose Logistic Models Body Mass Index Humans Vitamin D Young Adult Female Adult Risk Factors Cross-Sectional Studies Aged Male Middle Aged Exercise
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Development and Validation of an Algorithm to Identify Nonalcoholic Fatty Liver Disease in the Electronic Medical Record.

Digestive diseases and sciences Nov 4, 2015
BACKGROUND AND AIMS: Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. Risk factors for NAFLD disease progression and liver-related outcomes remain incompletely understood due to the lack of computa...
Adult Male Middle Aged Prevalence Cohort Studies Logistic Models Humans Algorithms Electronic Health Records Female Aged Alanine Transaminase Aspartate Aminotransferases International Classification of Diseases United States Triglycerides Diabetes Mellitus Natural Language Processing Biopsy Non-alcoholic Fatty Liver Disease Data Collection
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Identification of Type 2 Diabetes Risk Factors Using Phenotypes Consisting of Anthropometry and Triglycerides based on Machine Learning.

IEEE journal of biomedical and health informatics Feb 6, 2015
The hypertriglyceridemic waist (HW) phenotype is strongly associated with type 2 diabetes; however, to date, no study has assessed the predictive power of phenotypes based on individual anthropometric measurements and triglyceride (TG) levels. The ai...
Adult Cross-Sectional Studies Male Middle Aged Diabetes Mellitus, Type 2 Anthropometry Phenotype Retrospective Studies Female Risk Factors Aged Aged, 80 and over Triglycerides Humans Machine Learning
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Refining in silico simulation to study digestion parameters affecting the bioaccessibility of lipophilic nutrients and micronutrients.

Food & function Oct 23, 2014
Despite the considerable number of in vivo and in vitro studies on the digestive fate of lipophilic nutrients, micronutrients, and bioactives, the effects of the structure and composition of foods on the physicochemical mechanisms of luminal digestio...
Bile Acids and Salts Chemical Phenomena Digestion Viscosity Triglycerides Intestinal Absorption Lipolysis Dietary Fats Gastric Juice Triolein Models, Biological Caprylates Solubility Vitamin A Hydrophobic and Hydrophilic Interactions Humans Expert Systems Computer Simulation Animals Computational Biology Food Analysis
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