Pakistan journal of pharmaceutical sciences
Nov 1, 2023
Iron oxide nanoparticles (FeO NPs) stabilized with Moringa oleifera (M.O.) were successfully synthesized. The study aimed to explore the cytotoxic, anti-proliferative and anti-microbial potential of FeO NPs through various assays, including trypan bl...
Pakistan journal of pharmaceutical sciences
Nov 1, 2023
Scutellaria sibthorpii is used in treatment of bacterial infections, pains and inflammations. The leaf was extracted by maceration and then partitioned with hexane, ethyl acetate and n-butanol. The extract was screened for phytochemicals. The antioxi...
Pakistan journal of pharmaceutical sciences
Nov 1, 2021
Gingivitis is a condition that needs sustained concentration of antibiotic locally over extended period of time. The current study aimed to formulate and evaluate the sustained and localized release of metronidazole (MTZ) as mucoadhesive buccal table...
Pakistan journal of pharmaceutical sciences
Nov 1, 2020
The methanolic extract (SA-EXT) of Syzygium aromaticum flower buds and its fractions tested against three human cancer cell lines viz uterine cervix (HeLa), breast (MCF-7) and lung NCI (H-460) using sulforhodamine-B assay. The ethyl acetate soluble s...
Pakistan journal of pharmaceutical sciences
Nov 1, 2020
The objective of this study was to evaluate the effect of Foeniculum vulgare (FV) on fertility of mice and on serum sex hormone values of rats and rabbits. We used powdered form of Foeniculum vulgare seed and added it to food of mice, rats and rabbit...
Pakistan journal of pharmaceutical sciences
Nov 1, 2020
Prostate cancer is the second most common cancer in the world and the fifth cause of cancer deaths in men. Ciprofloxacin enables the inhabitation of the development of prostate cancer. In this regard, we plan to improve the anticancer effect of cipro...
Pakistan journal of pharmaceutical sciences
Nov 1, 2020
The stability of a mixture of methotrexate and dexamethasone sodium phosphate in 0.9% sodium chloride for intrathecal (IT) injection was assessed. To simulate the clinically used concentrations of the admixtures, 2mL of 0.9% sodium chloride was added...
Pakistan journal of pharmaceutical sciences
Sep 1, 2020
Emergence and spread of multidrug resistant (MDR) Staphylococcus aureus strains is becoming major challenge in treatment of soft tissue infections. This study aimed to explore antimicrobial and synergistic antimicrobial potential of three commerciall...
Pakistan journal of pharmaceutical sciences
Sep 1, 2020
Although ebastine (EBT) can impede histamine-induced skin allergic reaction and persuade long acting selective H1 receptor antagonistic effects but its poor water solubility circumscribed its clinical application. The main objective of this research ...
Pakistan journal of pharmaceutical sciences
Sep 1, 2020
This study aimed to diagnose the incidence of restless leg syndrome (RLS) in patients with diabetes mellitus (DM) type-2, thorough artificial intelligence based multilayer perceptron (MLP). 300 cases of diabetes mellitus type-2, of age between 18-80 ...