AIMC Topic: Disease Models, Animal
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Antiproliferative and anti-apoptotic effect of astaxanthin in an oxygen-induced retinopathy mouse model.
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
Apr 11, 2018
OBJECTIVE: To evaluate the impact of intravitreal (IV) and intraperitoneal (IP) astaxanthin (AST) injections on neovascular development (ND), retinal morphology, and apoptotic activity in a C57BL/6J mouse model with hyperoxia-induced retinopathy (HIR...
Autonomously Controlled Magnetic Flexible Endoscope for Colon Exploration.
Gastroenterology
Mar 9, 2018
Real-time estimation of lesion depth and control of radiofrequency ablation within ex vivo animal tissues using a neural network.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
Jan 4, 2018
BACKGROUND: Radiofrequency ablation (RFA), a method of inducing thermal ablation (cell death), is often used to destroy tumours or potentially cancerous tissue. Current techniques for RFA estimation (electrical impedance tomography, Nakagami ultrasou...
Subcutaneous cefazolin to reduce surgical site infections in a porcine model.
The Journal of surgical research
Dec 28, 2017
BACKGROUND: Surgical site infections (SSIs) pose a significant health and financial burden. A key aspect of appropriate prophylaxis is the administration of antibiotics intravenously (IV). However, subcutaneous administration of antibiotics is not we...
A novel method for the rapid detection of post-translationally modified visinin-like protein 1 in rat models of brain injury.
Brain injury
Dec 28, 2017
BACKGROUND: Although elevated serum levels of visinin-like protein 1 (VILIP-1), a neuron-specific calcium sensor protein, are associated with ischaemic stroke, only a single study has evaluated VILIP-1 as a biomarker of traumatic brain injury (TBI). ...
Combining robotic training and inactivation of the healthy hemisphere restores pre-stroke motor patterns in mice.
eLife
Dec 27, 2017
Focal cortical stroke often leads to persistent motor deficits, prompting the need for more effective interventions. The efficacy of rehabilitation can be increased by 'plasticity-stimulating' treatments that enhance experience-dependent modification...
Cupuaçu extract reduces nitrosative stress and modulates inflammatory mediators in the kidneys of experimental diabetes.
Clinical nutrition (Edinburgh, Scotland)
Dec 26, 2017
BACKGROUND & AIMS: We have previously reported an increased nitrosative stress in the kidneys of diabetic animals, which was reduced by an antioxidant probiotic. The present study evaluated whether the extract of cupuaçu (EC), an antioxidant compound...
Ultrasound Characterization of Bone Demineralization Using a Support Vector Machine.
Ultrasound in medicine & biology
Dec 25, 2017
We propose an ultrasound-guided remote measurement technique, utilizing an acoustic radiation force beam as our excitation source and a receiving hydrophone, to assess non-invasively a bone's mechanical properties. Features, such as velocity, were ex...
A Combination of Coffee Compounds Shows Insulin-Sensitizing and Hepatoprotective Effects in a Rat Model of Diet-Induced Metabolic Syndrome.
Nutrients
Dec 22, 2017
Since coffee may help to prevent the development of metabolic syndrome (MetS), we aimed to evaluate the short- and long-term effects of a coffee-based supplement on different features of diet-induced MetS. In this study, 24 Sprague Dawley rats were d...
Non-alcoholic Fatty Liver Disease
Alkaloids
Diterpenes
Caffeic Acids
Liver
Diet, High-Fat
Lipids
Coffea
Carbon-13 Magnetic Resonance Spectroscopy
Dietary Sucrose
Insulin
Time Factors
Insulin Resistance
Seeds
Rats, Sprague-Dawley
Disease Models, Animal
Metabolic Syndrome
Dietary Supplements
Cytokines
Animals
Blood Glucose
Intra-articular collagenase injection increases range of motion in a rat knee flexion contracture model.
Drug design, development and therapy
Dec 21, 2017
OBJECTIVES: A knee joint contracture, a loss in passive range of motion (ROM), can be caused by prolonged immobility. In a rat knee immobilization flexion contracture model, the posterior capsule was shown to contribute to an irreversible limitation ...
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